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    Glossary Hair Follicle Cells

    specialized cells responsible for hair growth and regeneration

    Hair follicle cells, also known as follicular cells, are specialized cells located within the hair follicle, the skin structure responsible for hair growth. These cells play a crucial role in the hair growth cycle, including the phases of growth (anagen), regression (catagen), and rest (telogen). They are involved in the production of keratin, the protein that makes up hair, and are essential for the regeneration and repair of hair.

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    1. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001 · 949 citations
    2. Characterization and isolation of stem cell-enriched human hair follicle bulge cells 2005 · 550 citations
    3. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons Proceedings of the National Academy of Sciences · 2005 · 419 citations
    4. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011 · 396 citations
    5. Nestin expression in hair follicle sheath progenitor cells Proceedings of the National Academy of Sciences · 2003 · 352 citations
    6. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009 · 330 citations
    7. Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves Proceedings of the National Academy of Sciences · 2005 · 319 citations
    8. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing Cell Reports · 2018 · 209 citations
    9. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    10. Noninvasive method for assessing the human circadian clock using hair follicle cells Proceedings of the National Academy of Sciences of the United States of America · 2010 · 166 citations
    11. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    12. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF Nature Communications · 2017 · 117 citations
    13. Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia British Journal of Dermatology · 2012 · 95 citations
    14. Gene expression profiling gets to the root of human hair follicle stem cells 2005 · 92 citations
    15. Epidermal stem cells and skin tissue engineering in hair follicle regeneration World Journal of Stem Cells · 2015 · 83 citations
    16. Neural Potential of a Stem Cell Population in the Hair Follicle Cell Cycle · 2007 · 80 citations
    17. Review of Hair Follicle Dermal Papilla cells as <i>in vitro</i> screening model for hair growth International Journal of Cosmetic Science · 2018 · 76 citations
    18. Inductive Properties of Hair Follicle Cells Annals of the New York Academy of Sciences · 1991 · 68 citations
    19. Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In vitro and Convert Hair Cycle In vivo Acta dermato-venereologica · 1998 · 64 citations
    20. From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells Cell Cycle · 2015 · 64 citations
    21. Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells Development · 1996 · 61 citations
    22. In vitro characterization of human hair follicle dermal sheath mesenchymal stromal cells and their potential in enhancing diabetic wound healing Cytotherapy · 2015 · 52 citations
    23. Perivascular Hair Follicle Stem Cells Associate with a Venule Annulus Journal of Investigative Dermatology · 2013 · 51 citations
    24. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle Cell Metabolism · 2020 · 51 citations
    25. Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats Gene · 2015 · 42 citations
    26. Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells Biochemical and biophysical research communications · 2012 · 38 citations
    27. Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence Cell reports · 2015 · 36 citations
    28. Paracrine crosstalk between human hair follicle dermal papilla cells and microvascular endothelial cells Experimental Dermatology · 2015 · 35 citations
    29. Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In vitro cellular & developmental biology. Animal · 2008 · 34 citations
    30. Multifaceted role of hair follicle dermal cells in bioengineered skins 2016 · 33 citations