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Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.

New methods help diagnose skin conditions caused by too much male hormone in women, like acne, hair loss, and excess hair growth.

Ring Chromosome 11 may be linked to conditions like early puberty, excessive hair growth, hair loss, and type 2 diabetes.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Lugol's solution can cause thyroid problems if used long-term for non-approved reasons.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Tissue-specific variation in mutant load complicates genetic counseling and prenatal diagnosis.

Proper diet management is crucial for phenylketonuria patients to avoid severe health issues.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

Finasteride potentially treats hair loss by reducing DHT production.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Raspberry ketone may help grow hair and improve skin elasticity.