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Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The first in-prison dermatology clinic in the U.S. faced challenges and found certain skin conditions common among inmates, with rare cases of serious skin cancer.

The document concludes that hirsutism in women, often caused by PCOS, requires systematic evaluation and can be treated with medications, mechanical removal, or cosmetic methods, with weight loss also being beneficial.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.

Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

SCD1 is crucial for skin health and overall energy balance.

The document concludes that managing PCOS effectively requires considering ethnic differences, obesity's impact, and ethical concerns in treatment approaches.

Phospholipase A2 enzymes play key roles in skin health and disease.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Vitamin D receptor is crucial for skin wound healing.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

High insulin levels are more common and a better predictor of carbohydrate issues in women with PCOS than glucose tolerance tests.

Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Vitamin D is crucial for skin health and managing skin diseases.

Children with metabolic syndrome often have skin problems like dark patches, skin tags, stretch marks, infections, acne, and psoriasis, which are linked to obesity and insulin resistance.

Vitamin A toxicity likely caused the patient's high calcium levels.

Fatp4 is crucial for healthy skin development and function.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Androgenic alopecia in men is mainly linked to family history, hormonal imbalances, and metabolic issues, but can also be influenced by lifestyle habits, environmental factors, and deficiencies in certain vitamins and microelements like copper.

Recognizing certain rashes can lead to earlier cystic fibrosis diagnosis and better outcomes.

TREM2 macrophages and unsaturated lipids contribute to acne inflammation.