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Hirsutism in women often indicates health issues like polycystic ovarian syndrome and is treated with lifestyle changes, medication, and cosmetic measures.

Girls conceived via assisted reproductive technologies show early puberty signs and larger ovaries.

Zinc, copper, and iron are important for skin health and may help diagnose skin diseases.

Low selenium levels worsen health but increase lifespan in mice.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Antiepileptic drugs can cause cosmetic side effects and affect menstrual cycles, fertility, and bone health in women with epilepsy.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Some people with lichen planus pigmentosus might later develop frontal fibrosing alopecia.

Vitamin D3 is important for bone health and may help treat various diseases beyond bone-related conditions.

Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The first in-prison dermatology clinic in the U.S. faced challenges and found certain skin conditions common among inmates, with rare cases of serious skin cancer.

The document concludes that hirsutism in women, often caused by PCOS, requires systematic evaluation and can be treated with medications, mechanical removal, or cosmetic methods, with weight loss also being beneficial.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.

Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

SCD1 is crucial for skin health and overall energy balance.

The document concludes that managing PCOS effectively requires considering ethnic differences, obesity's impact, and ethical concerns in treatment approaches.

Phospholipase A2 enzymes play key roles in skin health and disease.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Vitamin D receptor is crucial for skin wound healing.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.