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    Glossary Hair Keratinocytes

    specialized cells in hair follicles producing structural protein keratin

    Hair keratinocytes are specialized cells found in the hair follicle that produce keratin, a protein that forms the structural foundation of hair. These cells play a crucial role in the growth and strength of hair, as they continuously divide and differentiate to form the hair shaft.

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    1. Cyclosporin A-induced hair growth in mice is associated with inhibition of calcineurin-dependent activation of NFAT in follicular keratinocytes American Journal of Physiology-cell Physiology · 2003 · 57 citations
    2. Fructose-1,6-bisphosphate aldolase A levels decrease in hair keratinocytes during androgenetic alopecia International Journal of Dermatology · 2013 · 2 citations
    3. 1435 Enzymatic digestion of scalp hair follicle bulge allows to have more bulge-derived stem keratinocytes than explant isolation 2023
    4. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015 · 17 citations
    5. Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice Experimental Dermatology · 2018 · 10 citations
    6. Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes Journal of Photochemistry and Photobiology B-biology · 2018 · 9 citations
    7. α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity PloS one · 2020 · 7 citations
    8. Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte cytotoxicity Frontiers in Pharmacology · 2025 · 4 citations
    9. Cholesterol homeostasis in hair follicle keratinocytes is disrupted by impaired ABCA5 activity Biochimica and biophysica acta. Molecular and cell biology of lipids · 2023
    10. [Difference between the hair follicle cell and epidermal keratinocyte in vitro]. PubMed · 1990
    11. Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes 2021 · 11 citations
    12. Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes Frontiers in Cell and Developmental Biology · 2020 · 5 citations
    13. 085 Dermal papilla cells control hair follicle matrix keratinocytes proliferation through versican Journal of Investigative Dermatology · 2024
    14. Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    15. Characterization of response of murine hair follicle-derived keratinocyte against androgen and testosterone 5α-redactase activity Journal of dermatological science · 1994
    16. Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras‐dependent up‐regulation of KGF expression The FASEB Journal · 2003 · 51 citations
    17. Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells Experimental Dermatology · 2012 · 46 citations
    18. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    19. Potassium Channel Openers Stimulate DNA Synthesis in Mouse Epidermal Keratinocyte and Whole Hair Follicle Cultures Skin Pharmacology and Physiology · 1993 · 31 citations
    20. Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin Journal of Visualized Experiments · 2016 · 23 citations
    21. A model system to analyse the ability of human keratinocytes to form hair follicles Experimental Dermatology · 2014 · 15 citations
    22. Isolating Hair Follicle Stem Cells and Epidermal Keratinocytes from Dorsal Mouse Skin Journal of Visualized Experiments · 2016 · 13 citations
    23. Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation International journal of oncology · 2009 · 8 citations
    24. Effects of Platelet-Rich Plasma on Hair Growth using Artificial Intelligence-based Trichoscopy and Ki67+ Keratinocytes Analysis: A Randomized Placebo-Controlled Trial Clinical Dermatology Review · 2025
    25. Nestin as a marker of unipotent epithelial progenitor cells differentiate into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    26. Induction of hair follicles using neonatal mouse dermis and human keratinocytes: relevance for improved burn wound treatments Open University of Cape Town (University of Cape Town) · 2020
    27. Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells Experimental Dermatology · 2012 · 6 citations
    28. Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for <i>in vitro</i> hair follicle cloning PeerJ · 2016 · 18 citations
    29. Stimulatory Effect of Brazilian Propolis on Hair Growth through Proliferation of Keratinocytes in Mice Journal of Agricultural and Food Chemistry · 2014 · 18 citations
    30. 15-deoxy prostaglandin J2, the nonenzymatic metabolite of prostaglandin D2, induces apoptosis in keratinocytes of human hair follicles: a possible explanation for prostaglandin D2-mediated inhibition of hair growth Naunyn-Schmiedeberg's Archives of Pharmacology · 2016 · 11 citations