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    Did you mean Hair Follicle Stem Cells?
    Glossary Hair Follicle Stem Cells

    specialized cells in hair follicles that regenerate hair and skin

    Hair Follicle Stem Cells (HFSCs) are specialized cells located in the bulge region of hair follicles. They play a crucial role in the growth and regeneration of hair by periodically activating to produce new hair shafts and contribute to the repair of skin injuries. These cells have the unique ability to self-renew and differentiate into various cell types, making them essential for maintaining healthy hair and skin.

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    1. Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence Cell reports · 2015 · 36 citations
    2. The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse Stem cell research & therapy · 2022 · 2 citations
    3. The Stem Cell Quiescence and Niche Signaling is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse. Research Square (Research Square) · 2021
    4. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019 · 101 citations
    5. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence Nature · 2021 · 77 citations
    6. Atypical Protein Kinase C Isoform, aPKCλ, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence Journal of Investigative Dermatology · 2015 · 24 citations
    7. H2AK119ub dynamics control hair follicle stem cell quiescence Nature Communications · 2025 · 2 citations
    8. A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling iScience · 2023 · 1 citations
    9. 1438 KLF4 maintains hair follicle stem cell quiescence 2023
    10. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence Yearbook of pediatric endocrinology · 2021
    11. Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity eCommons (Cornell University) · 2013
    12. A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration Journal of Dermatological Science · 2016
    13. Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis Nature communications · 2016 · 31 citations
    14. Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration Digital Commons - RU (Rockefeller University) · 2025
    15. The incidental pore: Ca<sub>V</sub>1.2 and stem cell activation in quiescent hair follicles Genes & development · 2013 · 3 citations
    16. Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State Stem Cells · 2013 · 31 citations
    17. Roles of MED1 in Quiescence of Hair Follicle Stem Cells and Maintenance of Normal Hair Cycling 2012 · 16 citations
    18. Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa Journal of Clinical Investigation · 2020 · 33 citations
    19. Editorial: Hair Follicle Stem Cell Regeneration in Aging Frontiers in Cell and Developmental Biology · 2021 · 4 citations
    20. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    21. There and Back Again: Hair Follicle Stem Cell Dynamics Cell stem cell · 2011 · 4 citations
    22. Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging Frontiers in Aging · 2023 · 3 citations
    23. The Rho GTPase exchange factor Vav2 promotes extensive age-dependent rewiring of the hair follicle stem cell transcriptome Frontiers in cell and developmental biology · 2023
    24. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    25. State-dependent signaling by Ca<sub>v</sub>1.2 regulates hair follicle stem cell function Genes & development · 2013 · 27 citations
    26. The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function EMBO Reports · 2021 · 10 citations
    27. 1422 Uncoupling desmosomal cadherin adhesion activates quiescent hair follicle stem cells and orchestrates self-organized regeneration through outside-in signaling Journal of Investigative Dermatology · 2023
    28. 1392 Activation of Id2 gene regulatory network ruling quiescence of hair follicle stem cells Journal of Investigative Dermatology · 2018
    29. Autofluorescence in the Stem Cell Region of the Hair Follicle Bulge Journal of Investigative Dermatology · 2005 · 17 citations
    30. PIEZO1-mediated calcium signaling reinforces mechanical properties of hair follicle stem cells to promote quiescence Science Advances · 2025