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    Did you mean Hair Follicle Stem Cells?
    Glossary Hair Follicle Stem Cells

    specialized cells in hair follicles that regenerate hair and skin

    Hair Follicle Stem Cells (HFSCs) are specialized cells located in the bulge region of hair follicles. They play a crucial role in the growth and regeneration of hair by periodically activating to produce new hair shafts and contribute to the repair of skin injuries. These cells have the unique ability to self-renew and differentiate into various cell types, making them essential for maintaining healthy hair and skin.

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    1. Regulation of stem cell fate by HSPGs: implication in hair follicle cycling npj Regenerative Medicine · 2022 · 3 citations
    2. Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa Journal of the European Academy of Dermatology and Venereology · 2025
    3. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle Cell Metabolism · 2020 · 51 citations
    4. 1349 Inducing fate changes at the hair follicle stem cell nice Journal of Investigative Dermatology · 2023
    5. <i>N</i>1-acetylspermidine is a determinant of hair follicle stem cell fate Journal of Cell Science · 2021 · 17 citations
    6. Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model · 2017 · 3 citations
    7. Injury modifies the fate of hair follicle dermal stem cell progeny in a hair cycle‐dependent manner Experimental dermatology · 2019 · 16 citations
    8. Polyamine-controlled proliferation and protein biosynthesis are independent determinants of hair follicle stem cell fate bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
    9. 1360 Fate tracing of DNA-damaged hair follicle stem cells and their seno-differentiation clearance out of the niche 2023
    10. Editorial: Directing Stem Cell Fate Using Plant Extracts and Their Bioactive Compounds Frontiers in Cell and Developmental Biology · 2022 · 4 citations
    11. Gene expression profiling gets to the root of human hair follicle stem cells 2005 · 92 citations
    12. Fibronectin meshwork controls epithelial stem cell fate bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 2 citations
    13. Cellular dynamics in the niche of infrequently dividing hair follicle stem cells in the mouse Mus musculus eCommons (Cornell University) · 2010
    14. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    15. Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration Cell Cycle · 2015 · 47 citations
    16. The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury Cell Metabolism · 2025
    17. 1330 Flexible fate determination ensures robust differentiation in the skin hair follicle Journal of Investigative Dermatology · 2018
    18. The Force Is Strong with This One: Metabolism (Over)powers Stem Cell Fate Trends in cell biology · 2018 · 33 citations
    19. Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity eCommons (Cornell University) · 2013
    20. The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates Nature cell biology · 2023 · 6 citations
    21. 676 Wnt and SHH interact to determine hair follicle dermal condensate fate Journal of Investigative Dermatology · 2024
    22. Leek-Derived Exosome-like Nanoparticles Inhibit Hair Growth by Controlling the Differentiation Fate of Hair Follicle Stem Cells ACS Applied Bio Materials · 2026
    23. Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices Cell · 2017 · 214 citations
    24. Developmental Mechanisms Controlling Cell Fate, Evolution of Elsevier eBooks · 2016
    25. 1412 “Telescope model” for coordinated organ morphogenesis and stem cell formation 2023
    26. The Functions and Mechanisms of TGF‐β3 Signalling in Controlling the Fate Determinations of Various Types of Stem Cells Journal of Cellular Physiology · 2026
    27. Sox9 regulates melanocytic fate decision of adult hair follicle stem cells iScience · 2023 · 10 citations
    28. Molecular Mechanisms of Hair Follicle Development The Scientific World JOURNAL · 2024 · 4 citations
    29. 606 Connecting signaling dynamics with cell fates in live mice Journal of Investigative Dermatology · 2021
    30. Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate 2023 · 1 citations