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    Glossary hair follicle niche

    specialized skin microenvironment regulating hair growth and regeneration

    The hair follicle niche is a specialized microenvironment within the skin where hair follicles reside. It contains various cells, signaling molecules, and extracellular matrix components that work together to regulate hair growth, cycling, and regeneration. This niche plays a crucial role in maintaining the health and function of hair follicles, and disruptions in this environment can lead to conditions like alopecia.

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    1. Stem cell dynamics in the hair follicle niche Seminars in Cell & Developmental Biology · 2013 · 135 citations
    2. 1374 Cell-cell interaction in the hair follicle niche in androgenetic alopecia Journal of Investigative Dermatology · 2023
    3. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    4. Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons Aesthetic Plastic Surgery · 2018 · 22 citations
    5. Brief Report: Requirement of TACE/ADAM17 for Hair Follicle Bulge Niche Establishment Stem Cells · 2012 · 14 citations
    6. Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche Nature communications · 2023 · 1 citations
    7. Aging in hair follicle stem cells and niche microenvironment The Journal of Dermatology · 2017 · 38 citations
    8. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    9. Faculty Opinions recommendation of Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2020
    10. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011 · 283 citations
    11. The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015 · 66 citations
    12. 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium Mechanisms of Development · 2009
    13. Exploring Mechanical Niches Identified by Hair Follicle Compression and How These Transduce Proliferation and Differentiation Cues in Epidermally Derived cells. Durham e-Theses (Durham University) · 2019
    14. Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration <i>in vivo</i> The EMBO Journal · 2019 · 44 citations
    15. 440 Charting the Spatially Resolved Hair Follicle Stem Cell Niche: A Multi-Omics Atlas of Healthy and Diseased Scalp Journal of Investigative Dermatology · 2025
    16. Immune niches for hair follicle development and homeostasis Frontiers in physiology · 2024
    17. 687 BMP signaling in the hair follicle stem cell niche regulates hair growth and skin pigmentation 2016
    18. Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche The Journal of Pathology · 2013 · 220 citations
    19. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration Cell Stem Cell · 2018 · 43 citations
    20. Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration Digital Commons - RU (Rockefeller University) · 2025
    21. Reorganizing Niche Architecture Still Preserves Organ Function in the Hair Follicle bioRxiv (Cold Spring Harbor Laboratory) · 2022
    22. Cellular dynamics in the niche of infrequently dividing hair follicle stem cells in the mouse Mus musculus eCommons (Cornell University) · 2010
    23. The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches JCI Insight · 2023 · 6 citations
    24. Niche formed by bone morphogenetic protein antagonists gremlin 1 and gremlin 2 in human hair follicles Health Science Reports · 2022 · 5 citations
    25. Fate Before Function: Specification of the Hair Follicle Niche Occurs Prior to its Formation and Is Progenitor Dependent bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 2 citations
    26. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015 · 173 citations
    27. Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches Nature Communications · 2012 · 179 citations
    28. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020 · 77 citations
    29. Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche Science Immunology · 2024 · 21 citations
    30. The Hair Follicle Bulge: A Niche for Adult Stem Cells Microscopy and Microanalysis · 2011 · 19 citations