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Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.

MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

Dogs could be good models for studying human hair growth and hair loss.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Improving the environment and cell interactions is key for creating human hair in the lab.

Dental pulp stem cells might not reliably become neurons.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Different types of stem cells and their environments are key to skin repair and maintenance.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

ASH2L is essential for skin and hair development.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

Immune cells are essential for early hair and skin development and healing.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

Hair color is determined by melanin produced and transferred in hair follicles.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.