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    Glossary Hair Follicle Metabolism

    biochemical processes in hair follicles supporting growth and maintenance

    Hair Follicle Metabolism refers to the biochemical processes that occur within hair follicles to support hair growth and maintenance. This includes the conversion of nutrients into energy, the synthesis of proteins like keratin, and the regulation of cellular activities that influence the hair growth cycle. Understanding these processes is crucial for developing treatments for hair loss conditions such as alopecia.

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    1. Introducing Exogenous Energy From Hydrocolloid Wound Dressing Disrupting Human Hair Follicle Metabolism Research Square (Research Square) · 2022
    2. <i>In vitro</i> metabolism of progesterone by canine hair follicle cells Veterinary Dermatology · 2005 · 11 citations
    3. Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration Chinese Medicine · 2023 · 1 citations
    4. Dietary Vitamin D Supplementation Improves Hair Follicle Development and Affects Fatty Acid Metabolism in Rex Rabbits Food Science & Nutrition · 2025
    5. Natural product Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration Research Square (Research Square) · 2023
    6. Impaired Arginine Metabolism in Hair Follicles: A Potential Mechanism in Androgenetic Alopecia 2023
    7. Peroxisome Proliferator–Activated Receptor-γ−Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium Journal of Investigative Dermatology · 2018 · 17 citations
    8. Prostaglandin metabolism in human hair follicle Experimental Dermatology · 2007 · 65 citations
    9. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle Cell Metabolism · 2020 · 51 citations
    10. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming Experimental and Molecular Medicine · 2018 · 19 citations
    11. Sphingolipid metabolism orchestrates establishment of the hair follicle stem cell compartment The Journal of Cell Biology · 2025 · 4 citations
    12. LSD1 interacting with HSP90 promotes skin wound healing by inducing metabolic reprogramming of hair follicle stem cells through the c‐MYC/LDHA axis ˜The œFASEB journal · 2023 · 1 citations
    13. Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism Science Advances · 2023 · 1 citations
    14. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    15. Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma bioRxiv (Cold Spring Harbor Laboratory) · 2023
    16. 1332 Understanding the role of glycogen metabolism in human hair follicle biology Journal of Investigative Dermatology · 2018
    17. 762 Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism Journal of Investigative Dermatology · 2022
    18. The Metabolism of Dehydroepiandrosterone by Human Scalp Hair Follicles The Journal of Clinical Endocrinology & Metabolism · 1973 · 28 citations
    19. The Metabolism and Control Mechanism of Human Hair Follicles Current problems in dermatology · 2015 · 22 citations
    20. Hair Follicle Stem Cells Maintain the Differentiation Refractory Niche for Co-Occupant Melanocyte Stem Cells by Regulating Retinoid Metabolic Process Social Science Research Network · 2019
    21. Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire 2017 · 40 citations
    22. 1032 Characterization of the human scalp hair follicle microbiome reveals differential spatial distribution, abundance and viability of intrafollicular microbiota and modulation of hair growth and metabolism by staphylococcus epidermidis Journal of Investigative Dermatology · 2023
    23. Investigating the Role of Metabolism in Tissue Homeostasis and Tumor Initiation by Hair Follicle Stem Cells eScholarship (California Digital Library) · 2018
    24. Investigating the effects of metabolic dysregulation on hair follicles: a comparison of HIV‐infected women with and without central lipohypertrophy International Journal of Dermatology · 2013
    25. METABOLISM OF DEHYDROEPIANDROSTERONE BY ISOLATED HUMAN HAIR FOLLICLES European Journal of Endocrinology · 1971 · 7 citations
    26. 333 Poor perifollicular vascularization is associated with nutrient insufficiency and a quiescent metabolic phenotype in intermediate hair follicles from patients with female pattern hair loss Journal of Investigative Dermatology · 2021
    27. Methylene blue protects hair follicle stem cells from oxidative and metabolic stress to enhance hair regeneration Aging · 2026
    28. Human Hair Follicle Benzo[a]pyrene and Benzo[a]pyrene 7,8-diol Metabolism: Effect of Exposure to a Coal Tar-Containing Shampoo Journal of Investigative Dermatology · 1987 · 66 citations
    29. Intermediate Hair Follicles from Patients with Female Pattern Hair Loss Are Associated with Nutrient Insufficiency and a Quiescent Metabolic Phenotype Nutrients · 2022
    30. Influence of estrogens on the androgen metabolism in different subunits of human hair follicles. PubMed · 2001 · 41 citations