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    Glossary Hair Follicle Loss

    permanent destruction or degeneration of hair-producing skin structures

    Hair Follicle Loss refers to the permanent destruction or degeneration of hair follicles, which are the small structures in the skin responsible for hair growth. This condition can result from various factors, including genetic predisposition, autoimmune disorders like alopecia areata, or physical damage to the scalp. Once hair follicles are lost, they typically cannot regenerate, leading to permanent hair loss in the affected areas.

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    1. Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview Biomolecules · 2023 · 1 citations
    2. Pattern hair loss: Assessment of microinflammation in miniaturized and terminal hair follicles through horizontal histologic sections Journal of The American Academy of Dermatology · 2020 · 11 citations
    3. Strategies to utilize iPS cells for hair follicle regeneration and the treatment of hair loss disorders Elsevier eBooks · 2021
    4. Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil treatment in Brazilian female pattern hair loss patients Dermatologic Therapy · 2019 · 4 citations
    5. Do we need hair follicle stem cells and hair follicle neogenesis to cure common hair loss disorders? Hair transplant forum international · 2008 · 3 citations
    6. Hair Follicle Classification and Hair Loss Severity Estimation Using Mask R-CNN Journal of Imaging · 2022 · 4 citations
    7. Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata Frontiers in Medicine · 2026
    8. Anti-Hair Loss Activity of Healthy Human Scalp-Derived Staphylococcus capitis KMH304 Ferment Filtrate in Human Hair-Follicle Dermal Papilla and Keratinocyte Cells Microorganisms · 2026
    9. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    10. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005 · 92 citations
    11. Stem cells from human hair follicles: first mechanical isolation for immediate autologous clinical use in androgenetic alopecia and hair loss Stem cell investigation · 2017 · 86 citations
    12. Loss of Vascular Endothelial Growth Factor in Human Alopecia Hair Follicles Journal of Investigative Dermatology · 1995 · 47 citations
    13. Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. PubMed · 2003 · 26 citations
    14. Oral minoxidil bio‐activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss Journal of The European Academy of Dermatology and Venereology · 2019 · 9 citations
    15. Characterization of Hair Follicles in Hirosaki Hairless Rats with Deletion of Basic Hair Keratin Genes. Enlarged Medulla, Loss of Cuticle and Long Catagen Hirosaki University Repository for Academic Resources (Hirosaki University) · 2009 · 3 citations
    16. From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization Frontiers in Cell and Developmental Biology · 2026
    17. Hair Follicle Biology and Signaling in Female Pattern Hair Loss: A Neuroendocrine Biomarker Perspective Integrated With Artificial Intelligence–Driven Precision Diagnostics Dermatologic Therapy · 2026
    18. Hair Loss Treatment Uses Stem Cells to Generate Healthy New Follicles Genetic engineering & biotechnology news · 2022
    19. Hair loss improvement effect of Chrysanthemum zawadskii, peppermint and Glycyrrhiza glabra herbal mixture in human follicle dermal papilla cell and C57BL/6 mice Food Science and Technology · 2022
    20. HAIR LOSS ASSOCIATED WITH ESCITALOPRAM: DO SSRIs AFFECT MELATONIN AT THE HAIR FOLLICLE? Psychiatria Danubina · 2021
    21. 905 Dysfunction of hair follicle mesenchymal progenitors is associated with age-related hair loss 2019
    22. Apoptosis in follicles of individuals with female pattern hair loss is associated with perifollicular microinflammation International Journal of Cosmetic Science · 2016 · 30 citations
    23. 76532 Estetrol (E4) prolongs anagen in healthy and female pattern hair loss hair follicles ex vivo Journal of the American Academy of Dermatology · 2026
    24. Maintenance of optimised hair growth from viable terminal scalp hair follicles at baseline with oral finasteride in male pattern hair loss and first evidence of a “drug dependency” and a post-finasteride “rebound effect”. Skin Research and Technology · 2019 · 4 citations
    25. 333 Poor perifollicular vascularization is associated with nutrient insufficiency and a quiescent metabolic phenotype in intermediate hair follicles from patients with female pattern hair loss Journal of Investigative Dermatology · 2021
    26. The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth Zenodo (CERN European Organization for Nuclear Research) · 2026
    27. The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth Zenodo (CERN European Organization for Nuclear Research) · 2026
    28. <i>Pten</i> loss in Lgr5<sup>+</sup> hair follicle stem cells promotes SCC development Theranostics · 2019 · 24 citations
    29. Regenerative medicine and hair loss: how hair follicle culture has advanced our understanding of treatment options for androgenetic alopecia Regenerative Medicine · 2013 · 23 citations
    30. Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells Stem Cell Reports · 2017 · 20 citations