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    Glossary Hair Follicle Homeostasis

    balanced state of hair follicles cycling through growth and rest

    Hair follicle homeostasis refers to the balanced state of hair follicles, where they cycle through growth, rest, and shedding phases in a regulated manner. This balance is crucial for maintaining healthy hair density and preventing conditions like alopecia, where hair loss occurs due to disruptions in this cycle.

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    1. EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair Genes & Development · 2011 · 354 citations
    2. Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis Molecular Endocrinology · 2004 · 144 citations
    3. The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in the Hair Follicle Morphogenesis and Homeostasis American Journal of Pathology · 2006 · 9 citations
    4. Paxbp1 is Indispensable for the Maintenance of Hair Follicle Homeostasis Acta Dermato Venereologica · 2025
    5. The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    6. Type 2 innate immunity regulates hair follicle homeostasis to control <i>Demodex</i> pathosymbionts bioRxiv (Cold Spring Harbor Laboratory) · 2021
    7. Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells Developmental biology · 2007 · 25 citations
    8. Essential Role of STAT3 Signaling in Hair Follicle Homeostasis Frontiers in immunology · 2021 · 6 citations
    9. Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis Journal of Investigative Dermatology · 2026
    10. Hair follicle stem cells and intrafollicular homeostasis TURKDERM · 2014 · 1 citations
    11. Cholesterol homeostasis: Links to hair follicle biology and hair disorders Experimental Dermatology · 2019 · 25 citations
    12. Identification of novel glucocorticoid receptor-regulated genes involved in epidermal homeostasis and hair follicle differentiation The Journal of Steroid Biochemistry and Molecular Biology · 2007 · 19 citations
    13. Hair follicle morphogenesis and epidermal homeostasis in we/we wal/wal mice with postnatal alopecia Histochemistry and Cell Biology · 2014 · 7 citations
    14. Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model · 2017 · 3 citations
    15. Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis JCI Insight · 2025 · 1 citations
    16. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    17. Cholesterol homeostasis in hair follicle keratinocytes is disrupted by impaired ABCA5 activity Biochimica and biophysica acta. Molecular and cell biology of lipids · 2023
    18. Investigating the Role of Metabolism in Tissue Homeostasis and Tumor Initiation by Hair Follicle Stem Cells eScholarship (California Digital Library) · 2018
    19. Ceramide Synthase 4 Regulates Stem Cell Homeostasis and Hair Follicle Cycling Journal of Investigative Dermatology · 2015 · 53 citations
    20. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017 · 72 citations
    21. Ecological dynamics of <em>Malassezia</em> in the hair follicle homeostasis, dysbiosis, and disease iFungi · 2026
    22. Immune niches for hair follicle development and homeostasis Frontiers in physiology · 2024
    23. Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells Stem Cell Reports · 2017 · 20 citations
    24. Dynamics of Hair Follicle Morphogenesis and Skin Homeostasis Deep Blue (University of Michigan) · 2018
    25. Cyclic ADP-Ribose Modulates Intracellular Calcium Homeostasis and Anagen-Associated Signaling Pathways in Human Hair Follicle Dermal Papilla Cells Applied Sciences · 2026
    26. Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis 2014 · 42 citations
    27. Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis The EMBO Journal · 2021 · 25 citations
    28. Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth Pflügers Archiv - European Journal of Physiology · 2022
    29. Heparanase 1: a key participant of inner root sheath differentiation program and hair follicle homeostasis Experimental Dermatology · 2008 · 22 citations
    30. Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma Nature medicine · 2015 · 245 citations