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    Glossary Hair Follicle Cells

    specialized cells responsible for hair growth and regeneration

    Hair follicle cells, also known as follicular cells, are specialized cells located within the hair follicle, the skin structure responsible for hair growth. These cells play a crucial role in the hair growth cycle, including the phases of growth (anagen), regression (catagen), and rest (telogen). They are involved in the production of keratin, the protein that makes up hair, and are essential for the regeneration and repair of hair.

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    1. Repurposing DPP4-Inhibition to Improve Hair Follicle Activation and Regeneration Journal of Investigative Dermatology · 2023
    2. 755 Repurposing of DPP4 inhibition to improve hair follicle activation and regeneration Journal of Investigative Dermatology · 2022
    3. 362 Not just a cell marker: DPP4 modulates regeneration of hair follicles in large wounds Journal of Investigative Dermatology · 2021
    4. Treatment of MSCs with Wnt1a-conditioned medium activates DP cells and promotes hair follicle regrowth Scientific Reports · 2014 · 61 citations
    5. Application of a novel ingredient Blend promotes hair growth by modulating Wnt/β‐catenin signaling, DP inductivity, and boosting elastin expression in healthy human scalp hair follicles ex vivo Journal of Cosmetic Dermatology · 2026
    6. 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium Mechanisms of Development · 2009
    7. Exosomes derived from human dermal papilla cells promote hair growth in cultured human hair follicles and augment the hair‐inductive capacity of cultured dermal papilla spheres Experimental Dermatology · 2019 · 58 citations
    8. Generation and integration of hair follicle-primed spheroids in bioengineered skin constructs Biomedical Materials · 2022 · 8 citations
    9. 15-deoxy prostaglandin J2, the nonenzymatic metabolite of prostaglandin D2, induces apoptosis in keratinocytes of human hair follicles: a possible explanation for prostaglandin D2-mediated inhibition of hair growth Naunyn-Schmiedeberg's Archives of Pharmacology · 2016 · 11 citations
    10. Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege International Journal of Cosmetic Science · 2024
    11. Poly-D,L-Lactic Acid Filler Restores Hair Thickness and Shine by Ameliorating Age-Associated Follicular Decline International Journal of Molecular Sciences · 2026
    12. Novel Strategy for Hair Regeneration: Exosomes and Collagenous Sequences of Human a1(XVII) Chain Enhance Hair Follicle Stem Cell Activity by Regulating the hsa-novel-238a-CASP9 Axis Experimental Cell Research · 2025
    13. 1333 Spheroids cell cultures as a promising study model for hair follice regeneration Journal of Investigative Dermatology · 2018
    14. Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling Journal of Biological Chemistry · 2003 · 215 citations
    15. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005 · 417 citations
    16. Induction of transforming growth factor-beta 1 by androgen is mediated by reactive oxygen species in hair follicle dermal papilla cells Journal of Biochemistry and Molecular Biology · 2013 · 56 citations
    17. Establishment of an in vitro organoid model of dermal papilla of human hair follicle Journal of Cellular Physiology · 2018 · 44 citations
    18. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    19. Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells Journal of Investigative Dermatology · 2012 · 26 citations
    20. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    21. An In Vitro Model for the Morphogenesis of Hair Follicle Dermal Papillae Journal of Investigative Dermatology · 2013 · 10 citations
    22. All-trans-retinoic acid inhibits mink hair follicle growth via inhibiting proliferation and inducing apoptosis of dermal papilla cells through TGF-β2/Smad2/3 pathway Acta histochemica · 2020 · 10 citations
    23. Shh Gene Regulates the Proliferation and Apoptosis of Dermal Papilla Cells to Affect Its Differential Expression in Secondary Hair Follicle Growth Cycle of Cashmere Goats Animals · 2024 · 7 citations
    24. Extract of <i>Plumbago zeylanica</i> enhances the growth of hair follicle dermal papilla cells with down‐regulation of 5α‐reductase type II Journal of Cosmetic Dermatology · 2020 · 4 citations
    25. Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures Stem cells international · 2018 · 3 citations
    26. 2P-138 : Microencapsulated Hair Follicle Dermal Papilla Cell with Hyaluronic acid/Collagen hydrogel 한국공업화학회 연구논문 초록집 · 2020
    27. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014 · 149 citations
    28. Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo 2013 · 64 citations
    29. LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells Frontiers in Genetics · 2020 · 12 citations
    30. Scaffolds for epithelial and hair follicle regeneration Elsevier eBooks · 2019 · 1 citations