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    Glossary Hair Follicle Cells

    specialized cells responsible for hair growth and regeneration

    Hair follicle cells, also known as follicular cells, are specialized cells located within the hair follicle, the skin structure responsible for hair growth. These cells play a crucial role in the hair growth cycle, including the phases of growth (anagen), regression (catagen), and rest (telogen). They are involved in the production of keratin, the protein that makes up hair, and are essential for the regeneration and repair of hair.

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    1. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001 · 949 citations
    2. Characterization and isolation of stem cell-enriched human hair follicle bulge cells 2005 · 550 citations
    3. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons Proceedings of the National Academy of Sciences · 2005 · 419 citations
    4. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011 · 396 citations
    5. Nestin expression in hair follicle sheath progenitor cells Proceedings of the National Academy of Sciences · 2003 · 352 citations
    6. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009 · 330 citations
    7. Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves Proceedings of the National Academy of Sciences · 2005 · 319 citations
    8. Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth Proceedings of the National Academy of Sciences of the United States of America · 2013 · 256 citations
    9. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing Cell Reports · 2018 · 209 citations
    10. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003 · 208 citations
    11. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    12. Noninvasive method for assessing the human circadian clock using hair follicle cells Proceedings of the National Academy of Sciences of the United States of America · 2010 · 166 citations
    13. Hair follicle stem cells: Walking the maze European Journal of Cell Biology · 2007 · 165 citations
    14. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    15. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF Nature Communications · 2017 · 117 citations
    16. Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia British Journal of Dermatology · 2012 · 95 citations
    17. Gene expression profiling gets to the root of human hair follicle stem cells 2005 · 92 citations
    18. Epidermal stem cells and skin tissue engineering in hair follicle regeneration World Journal of Stem Cells · 2015 · 83 citations
    19. Neural Potential of a Stem Cell Population in the Hair Follicle Cell Cycle · 2007 · 80 citations
    20. Review of Hair Follicle Dermal Papilla cells as <i>in vitro</i> screening model for hair growth International Journal of Cosmetic Science · 2018 · 76 citations
    21. Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Re-Growth in Androgenetic Alopecia. Biomolecular Pathway Analysis and Clinical Evaluation Biomedicines · 2019 · 69 citations
    22. Inductive Properties of Hair Follicle Cells Annals of the New York Academy of Sciences · 1991 · 68 citations
    23. Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In vitro and Convert Hair Cycle In vivo Acta dermato-venereologica · 1998 · 64 citations
    24. From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells Cell Cycle · 2015 · 64 citations
    25. Hair follicle neogenesis induced by cultured human scalp dermal papilla cells Regenerative Medicine · 2009 · 63 citations
    26. Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells Development · 1996 · 61 citations
    27. In vitro characterization of human hair follicle dermal sheath mesenchymal stromal cells and their potential in enhancing diabetic wound healing Cytotherapy · 2015 · 52 citations
    28. Perivascular Hair Follicle Stem Cells Associate with a Venule Annulus Journal of Investigative Dermatology · 2013 · 51 citations
    29. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle Cell Metabolism · 2020 · 51 citations
    30. Cultured human and rat tooth papilla cells induce hair follicle regeneration and fiber growth Differentiation · 2004 · 48 citations