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    Glossary Anagen Hair Follicles

    phase where hair actively grows

    Anagen hair follicles, also known as growing hair follicles or active hair follicles, are in the phase of the hair growth cycle where the hair is actively growing. This phase can last anywhere from 2 to 7 years, during which the hair shaft is continuously produced by the follicle, resulting in longer hair. This is the most prolonged phase of the hair cycle and is crucial for determining the length of the hair.

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    1. Structural optimization of pep7, a small peptide extracted from epimorphin, for effective induction of hair follicle anagen Experimental Dermatology · 2005 · 9 citations
    2. ALKBH5 acts as a regulator of hair follicle telogen-to-anagen transition in mice Communications Biology · 2026
    3. Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling Stem Cells · 2019 · 20 citations
    4. Potential of Hair Follicle Stem Cell-Derived Exosomes Carrying miR-181a-5p to Promote the Telogen-to-Anagen Stage Aesthetic Plastic Surgery · 2026
    5. Anti-CXCL4 monoclonal antibody accelerates telogen to anagen transition and attenuates apoptosis of the hair follicle in mice Experimental and Therapeutic Medicine · 2017
    6. Prostanoid receptors in anagen human hair follicles Experimental dermatology · 2007 · 39 citations
    7. The balance of Bmp6 and Wnt10b regulates the telogen-anagen transition of hair follicles Cell Communication and Signaling · 2019 · 35 citations
    8. CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis Journal of Dietary Supplements · 2014 · 3 citations
    9. An estrogen receptor pathwayregulates thetelogen-anagen hair follicle transition andinfluences epidermal cell proliferation (epidermis/estrogen/keratinocyte/differentiation/mesenchymal 1996
    10. IL-15 Prolongs Anagen, Stimulates Proliferation, and Suppresses Apoptosis in the Hair Matrix of Human Scalp Hair Follicles Journal of Investigative Dermatology · 2023 · 9 citations
    11. Effects of platelet-rich plasma application on hair follicle count, telogen/anagen ratio, and miniaturized hair ratio in patients with androgenic alopecia: alone or in combination with other treatments Journal of Dermatological Treatment · 2025
    12. 1386 Estetrol prolongs anagen in healthy female scalp hair follicles by positively modulating dermal papilla functions and generation of progenitor stem cells ex vivo 2023
    13. FRI378 Estetrol Prolongs Anagen In Healthy Female Scalp Hair Follicles By Positively Modulating Dermal Papilla Functions And Generation Of Progenitor Stem Cells Ex Vivo Journal of the Endocrine Society · 2023
    14. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006 · 176 citations
    15. PDGF isoforms induce and maintain anagen phase of murine hair follicles Journal of Dermatological Science · 2006 · 136 citations
    16. Epimorphin acts to induce hair follicle anagen in C57BL/6 mice The FASEB Journal · 2003 · 24 citations
    17. Histochemistry of the human hair follicle with consideration of anagen phases I to VI Acta Histochemica · 1992 · 18 citations
    18. Oral Spermidine Supplementation Prolongs Hair Follicle Anagen Phase with Sustained Effects: A Randomized, Double-Blind, Placebo-Controlled Trial MEDS Public Health and Preventive Medicine · 2025
    19. 575 An extract of Leontopodium alpinum prolongs anagen phase in human hair follicles ex vivo Journal of Investigative Dermatology · 2021
    20. Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles Differentiation · 1994 · 130 citations
    21. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008 · 115 citations
    22. Morus alba Root Extract Induces the Anagen Phase in the Human Hair Follicle Dermal Papilla Cells Pharmaceutics · 2021 · 28 citations
    23. An important role of cutaneous lymphatic vessels in coordinating and promoting anagen hair follicle growth PLOS ONE · 2019 · 22 citations
    24. Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing BMC Genomics · 2022 · 8 citations
    25. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle The EMBO Journal · 2000 · 305 citations
    26. Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture Experimental Dermatology · 2009 · 132 citations
    27. Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice Scientific Reports · 2017 · 113 citations
    28. Integrated analysis of lncRNAs and mRNAs by RNA-Seq in secondary hair follicle development and cycling (anagen, catagen and telogen) of Jiangnan cashmere goat (Capra hircus) BMC Veterinary Research · 2022 · 24 citations
    29. Ephrin-A3 not only increases the density of hair follicles but also accelerates anagen development in neonatal mice Journal of Dermatological Science · 2008 · 15 citations
    30. Hair follicle transcriptome profiles during the transition from anagen to catagen in Cashmere goat (Capra hircus) Genetics and molecular research · 2015 · 14 citations