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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Overexpressing a specific enzyme in mice causes hair loss and female infertility.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.

The document suggests using natural remedies like bloodletting and honey for various health issues but lacks scientific evidence for their effectiveness.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

Lasers are effective and safe for various medical treatments, including cancer, wound healing, and skin conditions.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

People today have lower levels of arsenic, lead, cadmium, and iron in their hair than people did 100 years ago.

Finasteride may affect male fertility by interfering with specific sperm signaling.

Finasteride may cause infertility in rats by affecting epididymis and sperm function.

Disabling the FGF5 gene in sheep leads to longer wool.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

A specific protein in chicken embryos links early skin layers to feather development.

Many substances, including chemicals and metals, can cause skin reactions; careful handling and identification of allergens are crucial to prevent dermatitis.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

Finasteride exposure harms tadpole reproduction and hormone balance.

Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

ERG increases SOX9, promoting prostate cancer growth and invasion.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.

Ayurvedic treatment helped a woman with PCOS become pregnant and have a healthy baby.

The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.