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A new microneedle system with minoxidil nanoparticles effectively promotes hair regrowth with fewer side effects.

This study found that microneedles containing magnetic intracellular vesicles and tremella polysaccharide improved the hair microenvironment and accelerated hair regeneration in mice with androgenic alopecia.

This study found that cubosomes combined with dissolving microneedles enhanced transdermal penetration and hair growth efficacy of beta-sitosterol for treating alopecia.

This review highlights the promising potential of 3D printing for creating microneedles with precise customization and improved performance compared to traditional micromolding, emphasizing applications in personalized medical devices and advancements in biomedical fields.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.

This study found that using a stevioside-based microneedle patch significantly increased minoxidil's solubility and skin absorption, promoting hair growth in animal models and achieving 67.5% area coverage by day 35, highlighting the potential of this novel delivery system for androgenetic alopecia treatment.

This study developed a personalized microneedle that delivers finasteride directly to the skin, facilitating a sustained release and potentially reducing side effects associated with oral administration.

New microneedle method improves hair regrowth treatment delivery.

The treatment improved hair growth and thickness in most patients with minimal side effects.

Sabal serrulata and biomimetic peptides with microneedling reduced hair loss and improved hair thickness in men with balding.

This review of current research suggests that combining microneedling with minoxidil, and possibly platelet-rich plasma or mesotherapy, may achieve better hair growth results for androgenetic alopecia than conventional methods.

This study demonstrated that a new technology combining microneedle patches, stem cell exosomes, and light therapy effectively promoted hair regrowth in animal models within 7 days compared to conventional treatments.

This narrative review concluded that facial aging involves complex anatomical changes that require multimodal rejuvenation approaches, integrating fillers, collagen stimulators, botulinum toxin, and energy-based devices for effective results, while emphasizing the need for scientific evidence and patient safety in aesthetic treatments.

This study demonstrated that PRP treatment improved hair metrics in androgenetic alopecia, with the dermapen method proving more effective than the point-by-point technique for specific hair growth indicators.

This bibliographic review highlights the importance of microneedling as a dermatological technique for treating androgenetic alopecia, emphasizing its potential benefits and the need for personalized treatment by skilled dermatologists.

This review highlights the potential of microneedles for immunotherapy, emphasizing their ability to enhance immune responses and reduce side effects through precise and stimuli-responsive delivery, especially in tumor treatment, while also noting the limitations and areas for improvement in current systems.

This review highlights the potential of microneedle technology in traditional Chinese medicine as a promising transdermal delivery system for skin diseases, showcasing improved efficacy and reduced side effects of TCM ingredients while discussing the challenges of its clinical application.

This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.

This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.

This review examines the potential of swellable microneedles in drug delivery and diagnostics, highlighting innovations and challenges in their use for chronic disease treatment, but noting that issues like physiological responsiveness and long-term stability still require research.

This study explores the use of bioinspired 3D printed hollow microneedles, which may offer improved delivery of anti-wrinkle formulations, and reviews the current landscape and challenges of existing wrinkle treatments and microneedle technology.

This study found that microneedling monotherapy significantly increased hair count more than topical minoxidil in androgenetic alopecia, with combination therapy of microneedling and minoxidil being even more effective. Further research is needed to evaluate microneedling's safety and efficacy as a monotherapy.

This review highlights the potential of microneedles and nanomedicine in advancing tissue regeneration, emphasizing their innovative, localized, and minimally invasive approaches as promising solutions to current challenges in treating chronic wounds and degenerative diseases.

In this study, researchers developed a dissolvable microneedle patch containing baricitinib for alopecia areata treatment, reporting significantly higher hair growth in mouse models compared to controls, suggesting its potential as an effective, pain-free topical therapy.

This study found that a microneedle patch containing tofacitinib-loaded nanoparticles significantly increased hair follicle numbers and promoted hair regeneration with less drug compared to daily topical tofacitinib, suggesting it may be an effective strategy for alopecia treatment by reducing dosing frequency and enhancing drug delivery.

This study reported that using non-absorbable magnesium microneedle patches for 12 weeks improved under-eye wrinkles as measured by a grading scale and wrinkle index, with minimal discomfort and no significant change in dermal thickness.

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

This review discusses microneedling radiofrequency in cosmetic dermatology, particularly for skin texture improvement and various conditions, and reports no new clinical results.

A new microneedle system effectively delivers finasteride to treat hair loss.