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    Did you mean Gut-Skin Axis?
    Glossary Gut-Skin Axis

    The gut-skin axis refers to the bidirectional relationship between the gastrointestinal system and the skin, highlighting how gut health can influence skin conditions and vice versa. This connection is relevant to hair loss as imbalances in gut microbiota can lead to systemic inflammation and nutrient deficiencies, which may adversely affect hair growth and health. Key distinguishing characteristics include the role of probiotics, diet, and the immune system in maintaining both gut and skin health, suggesting that improving gut function may have beneficial effects on hair loss conditions.

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    1. Is there a ‘gut–brain–skin axis’? Experimental Dermatology · 2010 · 185 citations
    2. Gut microbes and skin disease, gut-brain-skin axis: A review Chinese Science Bulletin (Chinese Version) · 2017 · 3 citations
    3. The Gut-Brain-Skin Axis and Role of Intestinal Dysbiosis in Acne Vulgaris: Therapeutic Effects of Pro- and Prebiotic Use Elsevier eBooks · 2018 · 2 citations
    4. The brain–gut–skin axis in inflammatory and disfiguring skin diseases: mechanistic insights, clinical correlations, and therapeutic strategies Frontiers in Immunology · 2026
    5. Revisiting Rosacea Through the Skin–Gut–Brain Axis: A Neuroimmune Perspective Life · 2026
    6. Understanding the Association Between Mental Health and Hair Loss Cureus · 2025
    7. The gut‐microbiota‐brain axis: Focus on gut steroids Journal of Neuroendocrinology · 2024 · 8 citations
    8. Modulating the Gut–Skin Axis in Dermatological Diseases: Mechanisms and Clinical Applications of Probiotics, Prebiotics, Synbiotics, and Postbiotics International Journal of Clinical Dermatology · 2026
    9. Hair metal dysregulation in Parkinson’s disease: Implications for diagnosis and gut-brain axis involvement iScience · 2026
    10. Stress-related skin disorders Reviews in Endocrine and Metabolic Disorders · 2016 · 67 citations
    11. The Role of the Gut Microbiome and Microbial Dysbiosis in Common Skin Diseases International journal of molecular sciences · 2024 · 2 citations
    12. Emerging Trends and Focus in Human Skin Microbiome Over the Last Decade: A Bibliometric Analysis and Literature Review Clinical, Cosmetic and Investigational Dermatology · 2023
    13. Bioactive Compounds in Neurocosmetics: Bridging Nature-Derived Peptides and Synthetic Molecules for Advanced Skin Health and Well-being 2025
    14. The Mechanism and Research Progress of Skin Microbiota in Pathogenesis of Acne Dermatology Research and Practice · 2025
    15. Understanding the Impact of the Skin Microbiome on Dermatological Assessments and Therapeutic Innovation Dermato · 2025
    16. The Multi-Faceted Role of Gut Microbiota in Alopecia Areata Biomedicines · 2025 · 3 citations
    17. The Association Between Hidradenitis Suppurativa and Diet: An Update. PubMed · 2023 · 4 citations
    18. POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE Frontiers in Neuroendocrinology · 2023
    19. Role of the intestinal microbiota in the development of alopecia areata in celiac disease Vrach · 2023
    20. Melatonin’s Role in Hair Follicle Growth and Development: A Cashmere Goat Perspective International Journal of Molecular Sciences · 2025
    21. Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis Journal of Investigative Dermatology · 2026
    22. Nutritional and Microbial Strategies for Treating Acne, Alopecia, and Atopic Dermatitis Nutrients · 2024 · 15 citations
    23. The Gut-Scalp Axis: A Systematic Review of Dietary Interventions on Microbiome Dysbiosis in Scalp Disorders Journal of Pioneering Medical Science · 2025
    24. Parkinson's disease and skin 2021 · 28 citations
    25. Regulatory T cells in skin utilize the Cxcr4-Cxcl12 axis to promote hair follicle regeneration Cell Reports · 2025
    26. Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development Frontiers in Cell and Developmental Biology · 2020 · 12 citations
    27. Gut microbiome, metabolome and alopecia areata Frontiers in microbiology · 2023 · 2 citations
    28. Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice Frontiers in aging neuroscience · 2021 · 9 citations
    29. Probiotics in Dermatology: An Evidence-based Approach Indian Dermatology Online Journal · 2024 · 12 citations
    30. Pathomechanisms of immune-mediated alopecia International Immunology · 2019 · 45 citations