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This study observed that among patients with Myhre syndrome, those with the SMAD4 gene variant p.Arg496Cys experienced fewer symptoms like hearing loss, while those with the p.Ile500Thr variant often had severe aortic hypoplasia, highlighting the diverse symptom progression and genetic factors of this rare condition.

In this study, certain cysteine residues in Romney sheep wool fibers were labeled more often during stretching tests, particularly under wet conditions, suggesting variability in their disulfide bond contributions to fiber mechanics depending on hydration.

This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.

This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.

This review explores the potential of extracellular vesicle therapy as a novel strategy to delay intervertebral disc degeneration and enhance tissue repair, by modulating key pathogenic mechanisms, with a focus on the molecular components and bioengineering modifications of extracellular vesicles.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.

This study found that long-lived proteins in mice, identified across various tissues, may be linked to neurodegenerative and cardiovascular diseases due to their low renewal rate and increased risk of damage.

This review article summarizes recent advancements in biomimetic scaffolds, highlighting their promise in tissue engineering and personalized medicine, particularly for skin and musculoskeletal system regeneration, while emphasizing the need for more extensive research to ensure their safety for human use.

This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.

This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.

This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.

This study investigated the photoprotective properties of Brazilian pepper tree extract against UV-induced damage in skin cells, reporting that it enhanced expression of genes relevant to skin health and showed superior activity compared to standard antioxidants.

This study found that while parabens in haircare products were within legal limits, all samples contained dibutyl phthalate, raising concerns about chronic exposure to endocrine disruptors.

This study examined three olive oil formulations of baricitinib for topical delivery in treating alopecia areata, finding that Oil A showed the highest skin retention and maintained skin integrity without irritation, suggesting its potential for further investigation.

This review discusses recent advancements in the development and use of polymer-based nanohydrogels for topical drug delivery, noting their potential to enhance drug loading, release control, and skin penetration for treating dermatological conditions.

This review highlights the potential of regenerative medicine therapies, particularly stem cells, in treating a range of chronic diseases and injuries, while also discussing advancements and limitations in their application in Malaysia compared to other Asian countries.

This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.

In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.

In this study, researchers developed a GelMA-based gradient pH hydrogel that effectively reduced bacterial load and promoted fibroblast and endothelial cell proliferation, macrophage polarization, neovascularization, and hair follicle regeneration, offering a promising treatment for bacterially infected skin wounds.

This study suggests that human hair keratin-based gradient hydrogels incorporating silver ions may serve as promising dermal templates for wound healing, demonstrating favorable mechanical properties, cell interaction, and antibacterial activity.

In this study, researchers observed that during zebrafish fin regeneration, osteoblast Erk activity, influenced by Fgf receptor signaling, forms gradients scaling with amputation length, which predicts regenerative tissue growth and skeletal structure size.

This study used melamine formaldehyde particles to measure a pH gradient along the hair shaft, showing a significant pH decrease from the hair sheath to the external shaft.

Mesenchymal stiffness affects sweat gland cell development.

A new method improves the isolation of hair follicle cells for better hair growth research.

This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.

This study developed a bilayer bionic skin scaffold that mimics the skin's structure to resist microbial invasion and enhance wound healing, with in vivo animal studies showing improved collagen deposition, neovascularization, and hair follicle formation.

This study identified Activin A and follistatin as key regulators of hair cell differentiation in the mammalian auditory sensory epithelium, with Activin A signaling influencing the timing and pattern of cell differentiation.

This study found that a large number of pelage hair follicle mesenchymal stem cells can be efficiently isolated using two-step Ficoll Density Gradient Sedimentation, promoting hair growth by secreting exosomes in mice.

In this study, researchers developed a composite electrospun dressing with fiber gradient changes that mimics skin's natural structure, demonstrating enhanced wound healing, collagen deposition, and reduced fibrosis and scarring in both in vitro and in vivo experiments.