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Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Leydig cells can cause testosterone-secreting adrenal tumors in women.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Puberty involves complex hormonal changes, varies by gender and ethnicity, and requires careful monitoring for abnormalities.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

Higher early lead exposure is linked to delayed puberty in girls.

Treatment during development affects hormone balance and sexual behavior in male rats.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

Low selenium intake may delay puberty in boys but not in girls.