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Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Prolactin affects when mice shed and grow hair.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Finasteride affects young male rats' brain function and behavior negatively.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

A woman with acromegaloidism and normal growth hormone levels had a rare X-Tetrasomy, suggesting a need to study X-chromosome genes for their role in growth and facial development.

Excessive hair growth in women can be harmless or signal serious health issues, and treatment often includes medication and hair removal, with noticeable results after 3-6 months.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

Some skin diseases and their treatments can negatively affect male fertility.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.

About 20% of Japanese macaques had head alopecia, and stress and environment might cause hair loss.

An alpaca acted like a male and couldn't have babies because of a benign tumor in its ovary that caused high testosterone levels.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Androgens can cause hair growth in some areas but hair loss on the scalp.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.