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This study suggests that gender-affirming testosterone therapy in transgender men is generally safe and effective with adequate screening and monitoring, although high-quality long-term studies are lacking.

This review highlights that Cyproterone acetate combined with ethinylestradiol is highly effective for treating severe acne and hirsutism in women with hyperandrogenism, and it also provides benefits for cycle control and mood improvement, according to the analysis of 78 studies.

This review covers the pathophysiology, diagnosis, evaluation, and treatment of hirsutism and reports no new clinical findings.

This article reviews the causes and management of hirsutism, reports no new results, and emphasizes that prolonged pharmaceutical treatment is necessary for improvement.

This article presents guidelines developed by a multidisciplinary expert panel for the care of adolescent transgender and non-binary individuals with gender dysphoria, emphasizing individualized, affirmative care to enhance well-being and quality of life.

This review reports that transgender individuals undergoing hormonal therapy for gender transition face increased risks of cardiovascular disorders, brain tumors, changes in bone density, metabolic disorders, and other health issues, while highlighting the necessity of this therapy for gender transformation.

This review discusses polycystic ovary syndrome, emphasizing its broad range of manifestations and associations with risks like type 2 diabetes and cardiovascular events, but reports no new clinical results.

This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.

This publication reviews the World Professional Association for Transgender Health's Standards of Care for supporting transgender and gender nonconforming people, with adjustments needed for diverse global contexts and no new clinical results.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.

This review discusses the role of oestrogens in stimulating growth hormone secretion and influencing linear bone growth in children, and reports no new clinical results; the authors suggest that oestrogens play a key role in pubertal growth spurts for both genders.

This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.

This review examines the epidemiology, pathophysiology, diagnosis, and management strategies for non-classic congenital hyperplasia due to 21-hydroxylase deficiency, and provides evidence-based recommendations for its treatment and genetic counseling.

This article proposes a hypothesis that hyperandrogenemia is the final common pathway for developing adolescent PCOS and emphasizes the importance of reducing androgen levels to mitigate risks of metabolic syndrome, diabetes, and infertility in adulthood.

This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.

This review discusses medical treatments for hirsutism, focusing on oral contraceptives and other therapies, but reports no new results; the authors emphasize the lack of evidence for insulin sensitizers in treating hirsutism alone.

This review discusses oxidative stress's role in polycystic ovary syndrome and examines various biomarkers to understand its impact on the disorder's pathogenesis, but reports no new clinical results.

This review discusses the pathophysiology, molecular genetics, and management of non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, with no new clinical findings reported.

This review discusses the causes, clinical features, diagnostic approach, and treatment options for hirsutism in women, but reports no new findings.

This study found that finasteride significantly reduced hirsutism in women with idiopathic hirsutism or polycystic ovary syndrome over six months, suggesting its potential effectiveness for this condition.

This review explores potential indications for prolactin receptor inhibitors beyond breast and prostate cancers, emphasizing the need for potent antibodies to further research prolactin receptor expression.

This discussion proposes a model to incorporate patients with hormone-resistant prostate cancer into the existing framework by redefining hormone resistance and exploring new therapeutic approaches.

This review examines various androgen deprivation therapy methods for advanced prostate cancer, highlighting benefits and potential cardiovascular and sexual adverse effects, but reports no new clinical results.

This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.

This article provides a framework for understanding hair disorders and treatment options in transgender individuals undergoing hormonal therapy and reports no new clinical results.

This review examines hair and skin disorders in post-menopausal women and notes a lack of evidence supporting specific treatments for this population.

This article discusses the development of a transdermal testosterone patch for postmenopausal women to deliver physiological testosterone levels but reports no new clinical results, highlighting a need for long-term safety data.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

This article provides an endocrine perspective on evaluating and managing hirsutism but reports no new research findings.