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Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Adding hormone therapy to radiation improves survival for high-risk prostate cancer recurrence but has side effects.

Hirsutism is when women have too much hair growth, often due to a bit more androgen hormones and sensitive skin.

Certain hormone treatments can improve acne and related conditions in women.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

Serenoa repens (saw palmetto) may cause side effects like hot flashes in children and needs more research for safety in pediatric use.

Secondary amenorrhea has many causes and requires thorough evaluation to treat and restore menstrual cycles.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Higher testosterone and DHT levels are linked to hair loss in men, but not to prostate cancer risk.

Hirsutism causes significant psychological distress in women.

Hirsutism is often caused by high male hormone levels and can be treated with lifestyle changes and medications.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.