2 citations
,
January 2014 in “Springer eBooks” Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.
2 citations
,
July 2012 in “Obstetrics, gynaecology and reproductive medicine” This article reviews the physiology, causes, and treatments of hirsutism and reports no new research findings.
2 citations
,
January 2012 in “Journal of metabolic syndrome” This review summarizes current knowledge on the diagnosis and treatment of hirsutism but provides no new clinical results.
1 citations
,
August 2022 in “Veterinary medicine and science” This review discusses various diagnostic and treatment strategies for canine prostate diseases, including pharmacological options and advanced procedures, but reports no new clinical results.
1 citations
,
January 2018 in “Journal of Gynecologic Surgery” This article reports two cases where ovarian hyperthecosis caused hyperandrogenism in postmenopausal women, confirmed by imaging and resolved after bilateral oophorectomy.
1 citations
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March 2011 in “Informa Healthcare eBooks” Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
1 citations
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October 2009 in “Current psychiatry” This article discusses pharmacologic treatments for male sexual offenders, focusing on reducing sexual drive through nonhormonal or hormonal means, but it reports no new clinical results.
May 2026 in “Journal of Assisted Reproduction and Genetics” In this study, researchers developed and tested a novel peptide, AMHR2BP, which mimics the function of Anti-Müllerian hormone to protect ovarian follicles in mice, showing promise for preserving ovarian health during chemotherapy without causing toxicity.
February 2026 in “Cureus” In this case report, a 25-year-old transgender woman on testosterone-blocking therapy developed generalised hypertrichosis after starting ciclosporin for severe plaque psoriasis, illustrating that ciclosporin can induce this side effect even under androgen suppression.
October 2025 in “Journal of the Endocrine Society” In this case study, a 68-year-old woman with hyperandrogenism and presumed ovarian origin responded well to GnRH agonist therapy, normalizing testosterone levels and stabilizing blood pressure, suggesting its effectiveness as a non-surgical treatment option.
July 2024 in “Journal of Pediatric Endocrinology and Metabolism” This study presents two adolescent cases of ovarian hyperthecosis, a rare cause of severe hyperandrogenism, highlighting management strategies involving gonadotropin suppression and hormone replacement after excluding androgen-producing adrenal and ovarian tumors.
October 2022 in “Journal of the ASEAN Federation of Endocrine Societies” This study found that GnRH-a treatment or orchiectomy, which required significantly lower doses of oral estradiol valerate, were more effective than anti-androgens like spironolactone and finasteride in achieving target hormone levels in transgender females in India.
January 2019 in “Oncogen” This report suggests that for prostate cancer patients with cardiovascular disease, prescribing the GnRH antagonist degarelix may reduce cardiac events compared to using GnRH agonists, although prescribing should consider potential cardiac risks, particularly in patients with pre-existing conditions or older age.
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
September 2016 in “Gynecology Obstetrics and Reproductive Medicine” This review outlines the diagnostic criteria and management strategies for polycystic ovary syndrome, focusing on hyperandrogenism's cutaneous manifestations, such as hirsutism and acne, and describes treatments like oral contraceptives and antiandrogens to address these issues.
November 2010 in “Clin-Alert” Monitoring for adverse effects in clinical treatments is crucial.
September 2008 in “UK vet. Companion animal” This article updates on the medical management of benign prostatic hyperplasia in companion animals and reports no new clinical findings; the authors discuss existing treatments.
August 1996 in “Journal of Pediatric and Adolescent Gynecology” This article discusses the various manifestations and diagnostic challenges of polycystic ovarian syndrome and reviews its associated symptoms and clinical heterogeneity but reports no new clinical findings.
January 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This review discusses hormonal therapies for acne related to endocrine disorders and provides practical guidelines for managing hormonally influenced acne in clinical practice, but reports no new clinical results.
13 citations
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October 2006 in “Pediatrics in review” This review discusses the complexities and factors influencing the management of precocious puberty in children, concluding that genetic influences are more significant than environmental ones. It reports no new research findings.
1 citations
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July 2015 in “AACE clinical case reports” This case report details a postmenopausal woman with hyperandrogenism due to both adrenal adenoma and ovarian hyperthecosis, highlighting the effectiveness of hormonal suppression and venous sampling for diagnosis.
6 citations
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October 2024 in “Reviews in Endocrine and Metabolic Disorders” In this review, researchers found that while hyper- and hypoprolactinemia in PCOS patients are linked to metabolic changes, intermediate prolactin levels might be protective, but more robust prospective studies and clinical trials are needed to confirm these findings and develop treatments.
71 citations
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August 2019 in “The journal of sexual medicine” In this study, transgender adolescents treated with testosterone for a median of 12 months experienced effective virilization, including voice deepening and increased hair growth, but also showed decreased HDL cholesterol and BMD z-scores, and increased hematocrit, with no short-term safety issues reported.
42 citations
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September 2007 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.
October 2024 in “Journal of the Endocrine Society” This case report details a postmenopausal woman whose hyperandrogenism was attributed to ovarian stromal hyperplasia, ultimately resolved with bilateral salpingo-oophorectomy.
August 2016 in “Journal of Investigative Dermatology” This study found that dihydrotestosterone alters the balance of Wnt pathway regulators in dermal papilla cells, hindering hair follicle stem cell differentiation and contributing to hair follicle miniaturization.
5 citations
,
October 2014 in “Gynecological Endocrinology” This case study describes a 15-year-old girl with a Sertoli–Leydig cell tumor who showed high androgen levels and steroidogenic responses similar to patients with polycystic ovary syndrome before surgery.
1 citations
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September 2023 in “JCEM case reports” This case series observed the efficacy of GnRH analogues in diagnosing and treating various forms of ovarian hyperandrogenism, illustrating their role in symptom management without surgery, particularly for benign conditions and refractory androgen excess.
January 2020 in “Journal of South Asian Federation of Obstetrics and Gynaecology” In this case study, laparoscopic bilateral salpingo-oophorectomy was associated with reduced androgen levels and partial reversal of male-pattern hair loss in a postmenopausal woman with ovarian hyperandrogenism.
2 citations
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March 2011 in “Infertility” This review highlights that while lifestyle changes may help with many ovulatory disorders, oocyte donation is considered a viable option for patients who cannot undergo ovulation induction; it reports no new results.