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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

A new gene variant causes glucocorticoid resistance in a mother and son.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Skin health and diseases are closely linked to metabolic processes.

Analyzing bear poop helps measure their stress without harming them.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Genes related to calcium signaling and lipid metabolism are important for curly hair in Mangalitza pigs.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Mutations in certain receptors can cause diseases and offer new treatment options.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The case shows the difficulty in diagnosing certain conditions when standard tests are negative.

Skin symptoms can indicate endocrine disorders and have various treatments.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.