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This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.

This study found that intradermal reactivity to histamine in dogs varies with time of day, and glucocorticoids may influence this variation.

This study observed that inducible deletion of the Ugcg gene in mouse epidermis led to a significant reduction in GlcCers and epidermal POS-Cers, causing impaired skin barrier function and delayed wound healing.

Generalized glucocorticoid resistance causes hormone imbalances and varied symptoms due to gene mutations.

In this commentary, the authors discuss emerging evidence primarily from pharmacovigilance data and retrospective studies indicating a potential association between GLP-1 receptor agonists, like semaglutide and tirzepatide, and hair loss, although causality remains unproven, prompting recommendations for patient monitoring and further research.

In this study, the researchers found that glucocorticoid receptor activation may influence glucose metabolism, with preventive GR antagonist treatment reducing hyperglycemia and restoring glucose tolerance in a PCOS mouse model.

This study found that children with celiac disease who adhered to a gluten-free diet experienced significant improvements in height, weight, and symptoms like diarrhea and abdominal pain, although cases of abdominal distention increased.

This case report documents a cat with necrolytic migratory erythema due to glucagonoma and diabetes mellitus, highlighting similarities to glucagonoma syndrome in humans.

This review examines the clinical features, causes, diagnosis, and treatment of Chrousos syndrome but reports no new experimental findings on this condition.

This pilot study found that intradermal 10% glucose combined with non-cross-linked hyaluronic acid improved hair density and diameter more than hyaluronic acid alone in adults with androgenetic alopecia, with no serious adverse events.

This literature review highlights a potential but uncertain link between GLP-1 receptor agonist therapy for type 2 diabetes and obesity and hair loss, with variations among different medications.

This study developed and validated a method for measuring stress biomarkers in hair during pregnancy, finding that glucocorticoid levels increased over trimesters while endocannabinoid levels remained constant, suggesting hair analysis as a reliable tool for monitoring stress responses in pregnant women.

In this study, younger women with PCOS showed a 27% prevalence of abnormal glucose tolerance, with higher rates among those who are obese, have central adiposity, acanthosis nigricans, or a family history of diabetes.

This study reports conflicting evidence on whether GLP-1 receptor agonists are associated with various forms of alopecia, suggesting dermatology practitioners should consider monitoring and counseling patients using these medications.

This review reports that collagen as a nutraceutical shows promising results for improving skin health in estrogen-deficient women, but more research is needed for scalp hair, nail health, and optimal dosing of curcumin and glutathione.

In this study, pemphigus vulgaris patients treated with high-dose prednisolone developed symptoms similar to those seen in corticosteroma, such as weight gain and muscle weakness, with increased risks of arterial hypertension and glucose metabolism disorders after 6 months of therapy.

This review summarizes recent research into the effects of GLP-1 receptor agonists on skin processes, noting potential benefits for wound healing but also potential cosmetic concerns like facial fat loss and decreased collagen, highlighting the need for more clinical studies to clarify their dermatological impact.

This study introduced an innovative nanozyme system called MCP@G, which was shown to improve diabetic wound healing in rats by alleviating mitochondrial oxidative stress, enhancing fibroblast migration, and promoting blood vessel and hair follicle regeneration, offering a promising approach for treating challenging diabetic wounds.

In this case study, a 7-year-old boy with Down syndrome and alopecia areata experienced notable hair regrowth, improved gut function, and emotional stability with individualized homeopathic treatment, whereas prior allopathic approaches were ineffective.

In this case study, a 7-year-old boy with Down syndrome and conditions like alopecia areata and gluten intolerance showed hair regrowth, improved gut function, and emotional stabilization following individualized homeopathic treatment, succeeding where prior allopathic interventions failed.

This study reviewed preclinical evidence suggesting that topical glutamic acid can enhance hair regrowth and skin healing in burn-induced alopecia, highlighting its potential as a simple, low-cost treatment option that warrants further clinical trials.

In this study, cedrol was found to reduce lipid accumulation in the liver and adipose tissues of dexamethasone-treated mice by antagonizing glucocorticoid receptors, suggesting its potential utility in treating dexamethasone-induced lipid metabolism disorders.

This study suggests potential causal links between blood levels of glutamine, citric acid, glucose, various lipids, and lipoproteins with alopecia areata, finding glutamine may have a protective effect and noting no evidence of reverse causality. Further research is needed to validate these associations.

Alopecia Areata may involve reduced antioxidant defenses in hair follicles, affecting stem cell function.

This study found that glucagon-like peptide-1 receptor agonist therapy was independently associated with an increased incidence of non-scarring hair loss, including telogen effluvium and androgenic alopecia, in adults but not alopecia areata.

This case series highlights the risk of iatrogenic Cushing syndrome and adrenal insufficiency among immigrant patients using over-the-counter medications from other countries, which often contain hidden glucocorticoids marketed as vitamins, prompting clinicians to perform thorough medication histories for accurate diagnosis and management.

This review suggests that GLP-1 receptor agonists may improve various dermatologic conditions, but larger studies are needed to confirm these findings.

This systematic review found conflicting evidence on hair loss related to GLP-1 receptor agonists in adults with type 2 diabetes or obesity, with some studies noting hair regrowth and others reporting hair loss as a side effect. Further research is needed to understand this relationship.

This study found that adding cyclophosphamide to glucocorticoid treatment for pemphigus patients led to earlier remission, with 89.5% achieving remission within 4 months compared to 73.9% with glucocorticoids alone, suggesting significant steroid-sparing effects and improved clinical outcomes.

This review indicates that glucagon-like peptide-1 receptor agonists may be linked to hair loss, raising safety concerns despite the lack of definitive causal evidence.