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Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Aging causes skin stem cells to work less effectively.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Hair follicle regeneration needs special conditions and young cells.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

A special microbe helps plants absorb rock phosphate by growing on their root hairs.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.