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    Did you mean Glial Cell Line-Derived Neurotrophic Factor?
    Glossary Glial Cell Line-Derived Neurotrophic Factor

    promotes neuron survival and growth, especially dopamine-producing ones

    Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a protein that promotes the survival and growth of neurons, the cells responsible for transmitting information in the nervous system. It is particularly important for the maintenance and repair of certain types of neurons, including those that produce dopamine, which are crucial for motor control and are affected in diseases like Parkinson's.

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    Research 30 of 881

    1. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    2. Histone deacetylase inhibitors promote neurosteroid‐mediated cell differentiation and enhance serotonin‐stimulated brain‐derived neurotrophic factor gene expression in rat C6 glioma cells Journal of Neuroscience Research · 2009 · 35 citations
    3. Psychological stress impact neurotrophic factor levels in patients with androgenetic alopecia and correlated with disease progression World Journal of Psychiatry · 2024
    4. GDNF neurotrophic factor signaling determines the fate of dermal fibroblasts in wound‐induced hair neogenesis and skin regeneration Experimental Dermatology · 2022 · 2 citations
    5. The Impact of Growth Factors in Platelet‐Rich Plasma Combination Therapy for Androgenic Alopecia Dermatologic Therapy · 2024
    6. Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells BioMed research international · 2014 · 10 citations
    7. Investigating the synergic effects of valproic acid and crocin on BDNF and GDNF expression in epidermal neural crest stem cells Acta Neurobiologiae Experimentalis · 2020 · 10 citations
    8. Faculty Opinions recommendation of GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2021
    9. GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells npj regenerative medicine · 2020 · 7 citations
    10. Age‐associated decrease in GDNF and its cognate receptor GFRα‐1 protein expression in human skin International journal of experimental pathology · 2016 · 2 citations
    11. Reawakening GDNF's regenerative past in mice and humans Regenerative Therapy · 2022 · 1 citations
    12. The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells Cell proliferation · 2023 · 5 citations
    13. The effect of inflammatory cytokines on the risk of hypertrophic scar: A Mendelian Randomization Study Research Square (Research Square) · 2024
    14. Comparative gene expression analysis of nestin-expressing hair follicle-derived cells Scientific Reports · 2026
    15. In vitro Differentiation of Adipose-Derived Stem Cells into Hair Cell-Like Cells in Guinea Pigs Journal of Otology · 2007 · 3 citations
    16. Hair follicle stem cell-derived secretome protects astrocytes in an in vitro ischemia/reperfusion model Anatomy & Cell Biology · 2025
    17. Directing Rat Hair Follicle Stem Cells Toward Neuronal Lineage With Enhanced Trophic Factor Expression Advanced Biomedical Research · 2024
    18. Keratin Gel as Conduit Filler for Peripheral Nerve Regeneration on a Rat Sciatic Nerve Injury Model 2010
    19. Human hair keratins promote the regeneration of peripheral nerves in a rat sciatic nerve crush model Journal of Materials Science Materials in Medicine · 2019 · 36 citations
    20. Prospect of Stem Cell Conditioned Medium in Regenerative Medicine BioMed Research International · 2014 · 298 citations
    21. Combination of media, biomaterials and extracellular matrix proteins to enhance the differentiation of neural stem/precursor cells into neurons Acta Biomaterialia · 2012 · 25 citations
    22. Therapeutic potential of hair follicle-derived stem cell intranasal transplantation in a rat model of ischemic stroke BMC neuroscience · 2022 · 8 citations
    23. Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration Advanced functional materials · 2020 · 220 citations
    24. Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro Stem Cell Research & Therapy · 2023 · 4 citations
    25. Epithelial growth control by neurotrophins: leads and lessons from the hair follicle Progress in brain research · 2004 · 99 citations
    26. An Overview of Growth Factors as the Potential Link between Psoriasis and Metabolic Syndrome Journal of Clinical Medicine · 2023 · 6 citations
    27. Cells, growth factors and biomaterials used in tissue engineering for hair follicles regeneration Regenerative Therapy · 2022
    28. 4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration Biomedicines · 2022
    29. Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro Molecular Medicine Reports · 2017 · 5 citations
    30. Organoid‐Guided Precision Medicine: From Bench to Bedside MedComm · 2025 · 17 citations