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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.

Using neurohormones to control keratin can lead to new skin disease treatments.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.

Skin stem cells can help improve skin repair and regeneration.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

Neurohormones help control skin health and could treat skin disorders.

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

The document concludes that proper recognition and treatment of skin appendage disorders are important for management.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.