7 citations
,
January 2024 in “Burns & Trauma” This review discusses recent advancements in engineering sebaceous gland organoids for potential regenerative applications, highlighting strategies to create functionalized organoids but reports no new clinical results.
1 citations
,
June 2022 in “Frontiers in Neuroanatomy” This study found that neonatal blocking of androgen and estrogen pathways in rats altered sex-specific expression of estrogen and androgen receptors in adult pituitary and adrenal glands, potentially influencing lifelong neuroendocrine function.
August 2026 in “Cosmoderma” This review identifies sebaceous gland disorders as key indicators of hormonal imbalances, detailing how various hormones affect sebaceous function, and emphasizes a multidisciplinary approach to improve diagnosis and management by integrating endocrine, metabolic, and dermatologic insights.
9 citations
,
April 1985 in “Canadian Journal of Zoology” This study investigated the interdigital glands of moose, detailing their unique green hair coloration and the function of sebaceous and sweat glands, particularly during the rut period.
2 citations
,
January 2005 in “The Japanese Journal of Veterinary Dermatology” In this study, Pomeranians with non-illness, generalized alopecia did not exhibit adrenal or pituitary abnormalities, suggesting a breed-specific hormonal pattern as a potential cause rather than a functional adrenal anomaly.
1 citations
,
March 2009 in “The Journal of Urology” This review discusses trials on therapies for benign prostatic hyperplasia and reports that combination treatment is more effective than monotherapy for symptom relief and slowing disease progression in men with moderate to severe symptoms and enlarged prostate glands.
5 citations
,
June 2025 in “Journal of Functional Biomaterials” This study explored recent advancements in 3D bioprinting for head and neck defects, highlighting how bioinks and scaffolds may improve treatment customization and functionality by mimicking native tissue features. The research also examined challenges like biocompatibility and regulatory requirements on the path to clinical use.
77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
216 citations
,
May 2003 in “Journal of Investigative Dermatology” This study found that sebaceous-gland-derived glycerol significantly contributes to stratum corneum hydration in mice with sebaceous gland deficiencies.
57 citations
,
August 1999 in “Archives of dermatology” Hair follicles grow hair and release it through the skin.
December 2025 in “Toxicologic Pathology” This study outlines the complex structure and various functions of the skin, emphasizing its role as a barrier against external insults, a sensory receptor, and its importance in vitamin D synthesis.
147 citations
,
October 2004 in “Experimental dermatology” This paper reviews the role of androgens in human skin function and the challenges in developing treatments for androgen-associated disorders, reporting no new experimental results.
6 citations
,
April 1996 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” This study suggests that TGF-alpha may function in an autocrine or juxtacrine manner rather than promoting cell proliferation during hair growth cycles in ferrets and sheep.
198 citations
,
January 1998 in “Dermatology” This review discusses human sebocyte in vitro models for studying sebaceous gland function and control but reports no new clinical results, highlighting hormonal effects and the impact of retinoids on sebocyte activity.
26 citations
,
March 2018 in “Experimental Dermatology” This article argues that prolactin may have a role in sebaceous gland function and suggests it could be a potential target for treating skin conditions, but reports no new clinical findings.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.
305 citations
,
February 2007 in “Hormone and metabolic research” This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
12 citations
,
April 2019 in “Nature protocols” This study describes a protocol for generating a fully functional 3D integumentary organ system from murine induced pluripotent stem cells, including the formation of hair follicles and sebaceous glands that function in vivo.
3 citations
,
December 1975 in “PubMed” This study found that acid and alkaline phosphatases serve different functions in Beagle dog skin, with ALP primarily involved in growth processes and ACP in phospholipid breakdown.
October 2022 in “Chinese Journal of Dermatology” This study observed that skin dryness does not seem to indicate impaired epidermal barrier function, as there was no negative correlation between stratum corneum water content and transepidermal water loss.
5 citations
,
October 2021 in “Signal Transduction and Targeted Therapy” In this study, structural and functional brain abnormalities specific to visuospatial and somatosensory processing networks were observed in patients with anorexia nervosa, highlighting a critical role for the precuneus.
This review highlights the potential of 3D bioprinting in developing functional, patient-specific artificial skin, addressing limitations of traditional skin grafts and advancing regenerative medicine applications.
179 citations
,
June 2000 in “The American journal of pathology” This study reports that the asebia-2J mutation in mice affects sebaceous gland function and leads to hair follicle destruction, offering a model for human scarring alopecias.
10 citations
,
January 2014 in “Journal of prosthodontic research” This study found that while both natural and bioengineered salivary glands showed similar protein concentrations in response to taste stimulation, their protein compositions and amylase concentrations differed, which may affect nerve signal balance.
1 citations
,
December 2019 in “Medical Journal of Dr D Y Patil Vidyapeeth” This case report details a 26-year-old woman with a rare large functional adrenal myelolipoma, characterized by elevated hormone levels and requiring surgical intervention.
21 citations
,
November 2022 in “Frontiers in immunology” This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.
June 2026 in “Journal of Investigative Dermatology” Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.
February 2026 in “International Journal of Molecular Sciences” This study found that PDLLA filler treatment may help combat age-related hair thinning by reducing oxidative stress and enhancing hair follicle function in both cell and animal models.
291 citations
,
October 2005 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that rat whisker follicle stem cells can be expanded in culture and transplanted to form functional hair follicles, demonstrating their multipotency and potential for regenerative medicine.
62 citations
,
October 2017 in “JAMA facial plastic surgery” This study reported that using condensed nanofat combined with fat grafts significantly improved the aesthetic and functional aspects of atrophic facial scars in 20 patients, as assessed by both patients and plastic surgeons using the Patient and Observer Scar Assessment Scale.