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Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Conditions affecting sex development show that sexual diversity is a natural part of human variation.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

More research is needed to understand how testosterone is maintained in adult males.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

The document does not determine if adults with aphallia are fertile.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Hair transplantation is the best treatment for hair loss, with new technologies improving results, and stem cell and gene therapies may treat severe baldness in the future.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Exposure to the hair loss drug finasteride during pregnancy can cause genital anomalies in male babies, but not in female babies. It's best to avoid this drug in women who could potentially become pregnant.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

Sex hormones likely don't affect atopic dermatitis in adolescents and adults.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Higher early lead exposure is linked to delayed puberty in girls.

Low selenium intake may delay puberty in boys but not in girls.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Hair loss in women may have causes other than hormones.

The document concludes that syphilis has varied symptoms that are often missed, making clinical awareness crucial for diagnosis.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.