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    Glossary Gene Expression

    process where genetic information directs protein or RNA synthesis

    Gene expression is the process by which information from a gene is used to synthesize functional gene products, such as proteins or RNA. This process involves two main stages: transcription, where the DNA sequence of a gene is copied into mRNA, and translation, where the mRNA is used as a template to build proteins. Gene expression is tightly regulated to ensure that the right genes are expressed at the right times and in the right amounts, which is crucial for normal development, cellular function, and response to environmental changes.

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    1. Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes Molecular and Cellular Biology · 2006 · 226 citations
    2. Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter Journal of Investigative Dermatology · 2000 · 215 citations
    3. Gene expression profiling of intestinal regeneration in the sea cucumber BMC Genomics · 2009 · 106 citations
    4. Regulation of Keratin Gene Expression in Hair Follicle Differentiation<sup>a</sup> Annals of the New York Academy of Sciences · 1991 · 98 citations
    5. Gene expression profiling gets to the root of human hair follicle stem cells 2005 · 92 citations
    6. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    7. Sequence, expression, and evolutionary conservation of a gene encoding a glycine/tyrosine-rich keratin-associated protein of hair. Journal of Biological Chemistry · 1993 · 76 citations
    8. Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development General and Comparative Endocrinology · 2009 · 60 citations
    9. Gene Expression During Drosophila Wing Morphogenesis and Differentiation Genetics · 2005 · 57 citations
    10. Intermediate filaments: regulation of gene expression and assembly European journal of biochemistry · 1993 · 50 citations
    11. Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis Journal of Dermatological Science · 2004 · 47 citations
    12. Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice Journal of Biological Chemistry · 1997 · 44 citations
    13. Gene Expression of Mouse S100A3, a Cysteine-Rich Calcium-Binding Protein, in Developing Hair Follicle 1998 · 40 citations
    14. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog <i>Silurana tropicalis</i> Sexual Development · 2009 · 37 citations
    15. Differential gene expression analysis between anagen and telogen of Capra hircus skin based on the de novo assembled transcriptome sequence Gene · 2013 · 31 citations
    16. Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women Steroids · 2003 · 28 citations
    17. Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles Journal of Dermatological Science · 2013 · 27 citations
    18. Gene expression profiling analysis reveals fur development in rex rabbits (<i>Oryctolagus cuniculus</i>) Genome · 2017 · 23 citations
    19. Predictive Metagenomic Profiling, Urine Metabolomics, and Human Marker Gene Expression as an Integrated Approach to Study Alopecia Areata Frontiers in Cellular and Infection Microbiology · 2020 · 22 citations
    20. An out-of-lab trial: a case example for the effect of intensive exercise on rhythms of human clock gene expression Journal of circadian rhythms · 2013 · 21 citations
    21. Newborn infant skin gene expression: Remarkable differences versus adults PLoS ONE · 2021 · 20 citations
    22. Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy Experimental Dermatology · 2019 · 20 citations
    23. Peripheral blood gene expression in alopecia areata reveals molecular pathways distinguishing heritability, disease and severity Genes and Immunity · 2010 · 20 citations
    24. Molecular characterization, expression and methylation status analysis of BMP4 gene in skin tissue of Liaoning cashmere goat during hair follicle cycle Genetica · 2016 · 18 citations
    25. Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse Gene Expression Patterns · 2006 · 17 citations
    26. Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat PloS one · 2020 · 16 citations
    27. Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2 Biology · 2021 · 14 citations
    28. Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station PloS one · 2016 · 14 citations
    29. Gene Expression in Rat Dermal Papilla Cells: Analysis of 2529 ESTs Genomics · 2000 · 14 citations
    30. An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopecia Cell Cycle · 2017 · 12 citations