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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Different fibroblasts play key roles in skin healing and scarring.

Tofacitinib may help treat severe hair loss, but more research is needed.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Stem cells in hair follicles can become various cell types, including neurons.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Tiny needles with valproic acid can effectively regrow hair.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Researchers found 15 new genetic links to skin traits in Japanese women.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Melatonin improved mental health and metabolism in women with PCOS.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

STAT5 activation is crucial for starting the hair growth phase.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

DNA methylation changes are linked to hair growth cycles in goats.

Curcumin may be an effective and safer anticancer agent by regulating key cell pathways.