64 citations
,
January 2000 in “The Analyst” This study describes an efficient gas chromatography-mass spectrometry method for detecting estrone and 17 beta-estradiol concentrations in hair, finding differing levels in male and female samples.
38 citations
,
January 2013 in “Analyst” This study identified the main secondary metabolites in Ziziphus jujuba seeds and confirmed that UPLC-MS/MS and GC-MS effectively demonstrate their pharmaceutical quality.
30 citations
,
April 2011 in “Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry” This study found that using hair steroid profiling, dutasteride treatment led to reduced dihydrotestosterone levels and DHT/testosterone ratio in patients with male-pattern baldness.
17 citations
,
January 2013 in “Talanta” A new method was developed to accurately measure enzyme activity related to prostate health.
18 citations
,
March 2010 in “Therapeutic Drug Monitoring” This study developed a faster method to analyze fatty acid ethyl esters in human hair, potentially distinguishing alcohol consumption levels more efficiently.
7 citations
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May 2018 in “Indian Journal of Pharmacology” This study found that the methanolic extract of Carthamus caeruleus roots significantly reduced inflammation, promoted wound healing, and enhanced hair growth in experimental models, supporting its traditional use in Northern Algeria as a skincare remedy.
169 citations
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November 2009 in “The Journal of Clinical Endocrinology & Metabolism” This study found that prepubertal girls have significantly higher levels of estrogens and androgen metabolites compared to age-matched boys, which may contribute to their earlier onset of puberty.
![Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method](/images/assets/0026b639-99a8-455a-a986-c39aa65abfa9/small/2087.jpg)
20 citations
,
December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications” Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
1 citations
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November 2023 in “Endocrine Connections” This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.
158 citations
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January 2003 in “Journal of Forensic Sciences” This study demonstrates that a single exposure to GHB during a sexual assault can be detected by analyzing hair segments collected about one month after the incident.
128 citations
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January 1996 in “Journal of analytical toxicology.” This study suggests that while hair analysis using GC-MS is a sensitive method for detecting cocaine ingestion, it may not reliably indicate the amount, timing, or duration of drug use due to interindividual variability and multiple incorporation mechanisms.
56 citations
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January 1999 in “The Analyst” This study used gas chromatography-mass spectrometry to simultaneously quantify androstenedione, dihydrotestosterone, dehydroepiandrosterone, testosterone, androsterone, etiocholanolone, progesterone, and pregnenolone in human hair, detecting differences in steroid concentrations between male and female samples.
46 citations
,
November 2014 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that steroid deficiencies were significantly more severe in men with panhypopituitarism than in those with isolated gonadotropin deficiency.
33 citations
,
June 1995 in “International journal of legal medicine” This study observed that prolonged water or soil exposure can lead to significant reductions in drug levels in bleached and natural hair samples.
22 citations
,
September 2003 in “Journal of Investigative Dermatology” This study analyzed patients with X-linked dominant chondrodysplasia punctata and identified novel mutations in the emopamil-binding protein gene, highlighting the need for genetic testing alongside biochemical analysis for accurate diagnosis.
14 citations
,
July 2017 in “Monatshefte für Chemie - Chemical Monthly” This review discusses the analysis of pharmaceutical relics from prehistoric times to the twentieth century and emphasizes the need for a multifaceted approach, but it presents no new experimental results.
9 citations
,
June 2014 in “Nutrition and Cancer” This study found that hydro-alcoholic Eclipta alba extract may have anticancer and multidrug resistance-reversal effects in animal models, suggesting potential as an adjunctive agent in tumor chemotherapy.
8 citations
,
March 2012 in “Mass spectrometry letters” This study observed that the isotope-dilution GC-MS technique can assess 5α-reductase activity more effectively than conventional methods in rat liver S9 fractions, particularly at low testosterone levels.
7 citations
,
January 1990 in “Eisei kagaku” This study suggests that analyzing hair care product components left on hair using GC and GC-MS may provide a more objective forensic comparison than morphological examination.
5 citations
,
January 2021 in “Journal of Saudi Chemical Society” This study analyzed watercress oil and confirmed its phytochemical profile, UV absorption properties, and potential efficacy for hair growth, supporting traditional hot oil applications.
4 citations
,
November 2024 in “Scientific Reports” This study found that bioconjugating 16-methylheptadecanoic acid to damaged human hair can mimic the protective function of the original 18-methyleicosanoic acid, effectively restoring both the hair's external structural integrity and its internal moisture balance.
2 citations
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August 2004 This study found that early diagnosis using gas chromatography/mass spectrometry and appropriate long-term treatment are crucial for improving outcomes in patients with methylmalonic acidemia.
September 2026 in “Frontiers in Veterinary Science” This study found that the novel VG111 formulation alone healed canine wounds nearly twice as fast as the standard povidone–iodine treatment, achieving complete healing in 25 days compared to up to 50 days.
July 2026 in “Bandung Conference Series Pharmacy” This study found that rosemary oil from PT. Eteris Nusantara meets European Pharmacopoeia quality standards and is suitable for further hair growth pharmaceutical formulation.
November 2024 in “Research for Rural Development/Research for Rural Development (Online)” This study concluded that rosemary essential oil rich in terpenes was successfully extracted using vacuum-assisted hydrodistillation, and Solid Phase Micro Extraction was superior for identifying volatile compounds compared to direct injection.
This study utilized a novel mass spectrometry imaging technique to demonstrate that argan, avocado, and coconut oils are incorporated into hair fibers during cosmetic treatments, supporting their potential use in formulations for enhancing hair health and treating conditions like alopecia.
December 2023 in “Bulletin of Pharmaceutical Sciences Assiut” In this study, GC/MS analysis revealed variability in the quality of Syrian herbal formulations for BPH, with variations in tocopherol content, presence of parabens, and shortages of certain phytosterols.
February 2022 in “Indian Journal of Traditional Knowledge” In this study, a herbal oil formulation combining Hibiscus rosa-sinensis, Jasminum officinale, and Ficus benghalensis showed potential in reducing dandruff and promoting hair growth in affected individuals.
April 2018 in “Journal of Investigative Dermatology” This study found that sensitive scalp is characterized by increased pH levels, redness, altered sebum composition, and a disrupted microbiome, suggesting these features could inform treatment approaches.
14 citations
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May 2020 in “Drug Testing and Analysis” This study reports that hair analysis could potentially monitor metformin use in diabetic patients, suggesting a possible correlation between daily dose and concentration in dark hair but not in light hair.