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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Minoxidil effectively treats female pattern hair loss.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

High doses of finasteride cause cell growth and tumors in mice.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride shows promise for female hair loss, but more research needed.

Finasteride effectively treats hair loss in transgender men with few side effects.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

Finasteride effectively treats male hair loss, improving growth and density.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.