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    Glossary Follicular Route

    pathway for substances to penetrate skin via hair follicles

    The follicular route refers to the pathway through which substances can penetrate the skin via hair follicles. This route is significant in dermatology and pharmacology because hair follicles provide a direct channel to deeper layers of the skin, allowing for more efficient delivery of topical medications and treatments.

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    1. In Silico Study on the Contribution of the Follicular Route to Dermal Permeability of Small Molecules Pharmaceutical research · 2024
    2. Follicular transport route – Research progress and future perspectives European journal of pharmaceutics and biopharmaceutics · 2009 · 211 citations
    3. Applications and limitations of lipid nanoparticles in dermal and transdermal drug delivery via the follicular route European journal of pharmaceutics and biopharmaceutics · 2015 · 95 citations
    4. Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In vitro Human Skin Studies Skin pharmacology and physiology · 2018 · 35 citations
    5. Heat Enhanced Follicular Delivery of Isotretinoin to the Skin Pharmaceutical research · 2019 · 8 citations
    6. Penetration of drugs through skin, a complex rate-controlling membrane 2012 · 211 citations
    7. Nanocarrier Systems for Transdermal Drug Delivery InTech eBooks · 2012 · 13 citations
    8. The application of local hypobaric pressure — A novel means to enhance macromolecule entry into the skin Journal of Controlled Release · 2016 · 9 citations
    9. DETERMINATION OF PERMEATION PATHWAY OF GENTAMICIN INTO PIG’S EAR SKIN International research journal of pharmacy · 2015 · 3 citations
    10. Evaluation of Skin Penetration of Fluorescent Dissolved Formulations Using Confocal Laser Scanning Microscopy Pharmaceutics · 2025 · 2 citations
    11. ESTUDO DE PRÉ-FORMULAÇÃO DE SHAMPOO PARA TRATAMENTO DA ALOPECIA ANDROGENÉTICA CONTENDO CAFEÍNA COMO ATIVO Psicologia e Saúde em Debate · 2018 · 1 citations
    12. Penetration and Distribution in Human Skin Focusing on the Hair Follicle Drugs and the pharmaceutical sciences · 2005 · 1 citations
    13. NEW STRATEGIES FOR THE USE OF TOPICAL PRODUCTS IN THE TREATMENT OF ANDROGENETIC ALOPECIA International Journal of Health Science · 2022
    14. Polycystic Ovary Syndrome-Associated Acne: The Interplay of Hyperandrogenism, Insulin Resistance, and Therapeutic Strategies Cureus · 2025
    15. Pathophysiology and Complications of Polycystic Ovary Syndrome (PCOS): A Stepwise Visual Infographic Zenodo (CERN European Organization for Nuclear Research) · 2026
    16. Hair: A Review of Prominent Scalp Hair Changes throughout a Females’ Life Journal of Pigmentary Disorders · 2014
    17. Pathophysiology and Complications of Polycystic Ovary Syndrome (PCOS): A Stepwise Visual Infographic Zenodo (CERN European Organization for Nuclear Research) · 2026
    18. Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin Journal of Investigative Dermatology · 2005 · 64 citations
    19. Special Focus Issue: Transdermal, Topical and Folicular Drug Delivery Systems Drug Development and Industrial Pharmacy · 2016 · 5 citations
    20. Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study Pharmaceutical research · 2017 · 35 citations
    21. Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery Journal of Medicinal Chemistry · 2010 · 11 citations
    22. Vesicular Carriers for Follicular Drug Delivery Pharmaceutical Sciences · 2024 · 1 citations
    23. Follicular Penetration of Topically Applied Caffeine via a Shampoo Formulation Skin Pharmacology and Physiology · 2007 · 93 citations
    24. Investigation of Follicular and Non-follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles Pharmaceutical research · 2012 · 47 citations
    25. Percutaneous Drug Delivery to the Hair Follicle Informa Healthcare eBooks · 2005 · 1 citations
    26. Elevated serum androstenedione is associated with a more severe phenotype in women with polycystic ovary syndrome (PCOS) Hormones · 2014 · 28 citations
    27. Inverse micellar sugar glass (IMSG) nanoparticles for transfollicular vaccination Journal of controlled release · 2015 · 38 citations
    28. Cutaneous Drug Delivery: An Update Journal of Investigative Dermatology Symposium Proceedings · 2013 · 25 citations
    29. Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles Pharmaceutics (Basel) · 2023 · 4 citations
    30. Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles Pharmaceutical research · 2012 · 43 citations