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This case report describes a unique instance of late-onset Björnstad syndrome in an 18-year-old female, mimicking androgenetic alopecia, and indicates potential improvement with JAK inhibitor baricitinib, highlighting the need for considering this syndrome in similar cases of patterned hair loss in young individuals.

Scarring alopecia involves increased immune cells and specific gene changes near damaged hair follicles.

This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.

In this case study, an 11-month-old cat developed non-pruritic hair loss in the dorso-lumbar area after a road accident, with histopathological examination revealing post-traumatic changes such as absence of hair follicles and pyogranulomas.

This study reports that CD200R expression is significantly reduced in an experimental mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.

This review discusses the various trichoscopic features of androgenetic alopecia and alopecia areata, noting white dots in advanced cases as indicators of poor prognosis, but reports no new clinical results.

This study found that fibrosis-associated trochanters in central centrifugal cicatricial alopecia are enriched with hair follicle stem cells and may indicate a disrupted stem cell niche contributing to scarring.

This study suggests that pseudopelade may be an autonomous disease based on its distinctive clinical and histopathological features not present in other scarring alopecias.

This case report describes a young man who suffered from secondary cicatrical alopecia due to a steam cap burn at a hair salon, with no improvement after 13 months of various treatments until surgical excision.

This article discusses the management of male androgenetic alopecia and reports no new clinical results; it highlights the role of psychological and technical factors and the potential of combination treatments.

This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.

Early diagnosis of frontal fibrosing alopecia is crucial to prevent permanent hair loss.

This review suggests that hair transplantation may be a viable treatment option for certain primary scarring alopecias, although findings should be interpreted cautiously due to possible publication bias favoring positive results.

This research analyzed 72 primary scarring alopecia cases in a Barcelona hospital, finding that the majority involved women, with a lymphocytic infiltrate and subacute onset in many cases, leading to stable disease, while neutrophilic cases had more acute episodes.

In this study, researchers identified significant differences in protein expression patterns in scalps affected by central centrifugal cicatricial alopecia, notably upregulation of immune pathways and fibrosis markers and downregulation of metabolic proteins, suggesting unique disease mechanisms and potential therapeutic targets.

This prospective study in Morocco reported on 20 cases of frontal fibrosing alopecia, finding that dermoscopy played a key role in diagnosing and managing the condition, which can increasingly affect premenopausal women.

This article discusses contact dermatitis linked to alopecia and hyperpigmentation, but it reports no new clinical results.

Treating primary cicatricial alopecia is difficult and requires evidence-based methods.

This review discusses the links between different types of alopecia and thyroid disorders, highlighting some shared autoimmune factors, but reports no new clinical results.

In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.

This review suggests that 308 nm excimer therapy may offer a well-tolerated non-pharmacologic option for alopecia areata, with more limited evidence for its effectiveness in lichen planopilaris and frontal fibrosing alopecia.

This study investigated a unique frontal fibrosing alopecia-like presentation of alopecia areata, finding that patients experienced an insidious, chronic course with limited scalp hair regrowth, and showed a lower response to systemic corticosteroids compared to patchy alopecia areata.

This article notes the lack of US prevalence data for primary lymphocytic cicatricial alopecias due to the recent introduction of subtype-specific ICD-10 codes and highlights the importance of early diagnosis for hair preservation.

This study provides a framework for understanding different types of alopecias based on immune privilege collapse at specific follicular sites, revealing distinct patterns in immune effector programs and stromal influences depending on the alopecia type.

This review found that hair transplantation in patients with primary cicatricial alopecias is a viable option when the disease is stable, with outcomes varying significantly by subtype.

This study found that patients with primary cicatricial alopecia are at higher risk of developing various comorbidities, including systemic lupus erythematosus, hypothyroidism, and dermatological conditions, compared to controls.

This study reported that the combination of tacrolimus, clobetasol, and minoxidil improved hair measurements and stabilized inflammation in primary cicatricial alopecia patients, with most tolerating the treatment well.

In this case report, a 74-year-old woman with progressive alopecia unresponsive to minoxidil was diagnosed with Graham-Little-Piccardi-Lassueur Syndrome, illustrating the value of interdisciplinary collaboration in primary care for accurate diagnosis and improved patient outcomes.

In this retrospective study, oral minoxidil was found to improve the density of the frontotemporal hairline in 45.1% of patients with frontal fibrosing alopecia, with some also experiencing eyebrow and eyelash growth; however, adverse effects such as hypertrichosis were noted in 33.6% of the participants.

This study observed that while anomalous adipose tissue and displaced eccrine glands were common in certain types of scarring alopecia, these findings did not assist in diagnosis.