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    Glossary Fibroblast Growth Factor 5

    protein that inhibits hair growth by signaling phase transition

    Fibroblast Growth Factor 5 (FGF5) is a protein that plays a crucial role in regulating the hair growth cycle. Specifically, it acts to inhibit hair growth by signaling the transition from the growth phase (anagen) to the regression phase (catagen), which can lead to shorter hair growth periods and potentially contribute to conditions like alopecia.

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    Research 30 of 1000+

    1. 854 Dermal fibroblasts enhance growth factors production by androgens, and modulate keratinocyte proliferation and differentiation 2018
    2. Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin International Journal of Molecular Sciences · 2022 · 7 citations
    3. 516 Intrinsic factors regulating hair growth: insights into growth factors, cytokines, chemokines, and interferons Journal of Investigative Dermatology · 2024
    4. Therapeutic effects of growth factor cocktail (CellcurinTM) containing FGF5s (fibroblast growth factor 5 short) and NMN (nicotinamide mononucleotide) in patients with androgenetic alopecia: A split study Global dermatology · 2020
    5. Therapeutic Effects of Growth Factor Cocktail Including Fibroblast Growth Factor 9 in Patients with Pattern Hair Loss Journal of Clinical Dermatology · 2017
    6. LncRNA RP11-818O24.3 regulates proliferation and differentiation of hair follicle stem cells by targeting FGF2/PI3K/AKT pathway PLoS ONE · 2025 · 1 citations
    7. LncRNA RP11-818024.3 Promotes Hair-Follicle Recovery Via FGF2-PI3K/Akt Signal Pathway SSRN Electronic Journal · 2022
    8. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis Developmental dynamics · 1998 · 252 citations
    9. 839 Spatiotemporal antagonism in mesenchymal-epithelial Signaling in sweat versus hair fate decision Journal of Investigative Dermatology · 2017
    10. Growth Factor Cocktail Including Fibroblast Growth Factor 9 (Cellcurin) in the Treatment of Androgenetic Alopecia in Men and Women: A Randomized Controlled Trial International journal of trichology · 2023
    11. Clinical observation of basic fibroblast growth factor (bFGF) combined with minoxidil in the treatment of male androgenetic alopecia Journal of Cosmetic Dermatology · 2022
    12. Evaluation of platelet‐rich plasma plus basic fibroblast growth factor combined with minoxidil in the treatment of androgenetic alopecia: A randomized controlled trial Journal of Cosmetic Dermatology · 2023
    13. Expression ofWise in chick embryos Developmental Dynamics · 2007 · 6 citations
    14. Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene. Molecular Endocrinology · 1994 · 24 citations
    15. Effect of laser diode light irradiation on growth capability of human hair follicle dermal papilla cells 2017 · 8 citations
    16. Recent Advances in the Role of Fibroblast Growth Factors in Hair Follicle Growth Biomolecules · 2025
    17. Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction Trends in Cell Biology · 2014 · 119 citations
    18. Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics Journal of the American Academy of Dermatology · 2011 · 232 citations
    19. Hair growth is promoted by BeauTop via expression of EGF and FGF‑7 Molecular Medicine Reports · 2018 · 7 citations
    20. Combination therapy with topical minoxidil and nano-microneedle-assisted fibroblast growth factor for male androgenetic alopecia: a randomized controlled trial in Chinese patients Chinese Medical Journal · 2020 · 6 citations
    21. Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue<sup>1</sup> The Journal of Clinical Endocrinology & Metabolism · 1998 · 4 citations
    22. Regenerative cosmetology in dermatological practice: the use of exosomes and growth factors in skin regeneration Medicine Today and Tomorrow · 2025
    23. Hair Growth Promotion Activity and Its Mechanism of<i>Polygonum multiflorum</i> Evidence-based Complementary and Alternative Medicine · 2015 · 24 citations
    24. Growth kinetics of cultured dermal papilla cells and dermal sheath cells from human hair follicles Acta Academiae Medicine Militaris Tertiae · 2000
    25. 870 Y27632 promotes proliferation via EGFR signaling in a newly isolated and characterized human primary sebocyte cell line Journal of Investigative Dermatology · 2019
    26. Fibroblast Growth Factor Influences the Development and Cycling of Murine Hair Follicles Developmental Biology · 1993 · 58 citations
    27. Fibroblast growth factor and epidermal growth factor in hair development 1993 · 39 citations
    28. Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling Frontiers in bioengineering and biotechnology · 2022 · 8 citations
    29. Mechanical Stretching Can Modify the Papillary Dermis Pattern and Papillary Fibroblast Characteristics during Skin Regeneration Journal of Investigative Dermatology · 2022 · 19 citations
    30. Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment Inflammation and Regeneration · 2020 · 17 citations