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    Glossary FGF signaling

    fibroblast growth factors bind to receptors, triggering cellular processes

    FGF signaling, or Fibroblast Growth Factor signaling, is a biological pathway where fibroblast growth factors bind to their receptors on cell surfaces, triggering a cascade of cellular processes. This pathway is crucial for various functions, including cell growth, wound healing, and development of tissues and organs. In the context of hair, FGF signaling plays a significant role in hair follicle development and regeneration.

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    1. FGF signaling is required for initiation of feather placode development Development · 2004 · 66 citations
    2. FGF signaling for hair cycle resting phase alleviates radiation alopecia Journal of Dermatological Science · 2016 · 1 citations
    3. BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin PLoS Genetics · 2014 · 84 citations
    4. Sprouty/FGF signaling regulates the proximal–distal feather morphology and the size of dermal papillae Developmental Biology · 2012 · 50 citations
    5. Activation of EGF and FGF signaling in developing mouse skin inhibits hair follicle morphogenesis 2007
    6. Cooperation of TGF‐β and FGF signalling pathways in skin development Cell Proliferation · 2023 · 23 citations
    7. Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties Frontiers in Veterinary Science · 2023 · 5 citations
    8. 839 Spatiotemporal antagonism in mesenchymal-epithelial Signaling in sweat versus hair fate decision Journal of Investigative Dermatology · 2017
    9. FGF18 signaling determines radioresistance of telogen hair follicles by the arrest of hair cycling Journal of dermatological science · 2016
    10. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    11. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling Biomolecules & Therapeutics · 2016 · 26 citations
    12. <i>Eclipta prostrata</i> promotes the induction of anagen, sustains the anagen phase through regulation of FGF-7 and FGF-5 Pharmaceutical Biology · 2019 · 7 citations
    13. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    14. Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction Trends in Cell Biology · 2014 · 119 citations
    15. Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration PloS one · 2016 · 21 citations
    16. Androgenetic alopecia: combing the hair follicle signaling pathways for new therapeutic targets and more effective treatment options Expert Opinion on Therapeutic Targets · 2019 · 19 citations
    17. Hairy tale of signaling in hair follicle development and cycling Seminars in cell & developmental biology · 2012 · 161 citations
    18. Feather arrays are patterned by interacting signalling and cell density waves PLoS Biology · 2019 · 133 citations
    19. Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells 2007 · 66 citations
    20. Nitrate Promoting Hair Growth Through Enhancing Wnt/β-catenin and Downregulating TGF-β/Samd/BMP signaling pathway in C57BL/6 Mice bioRxiv (Cold Spring Harbor Laboratory) · 2024
    21. Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle ˜The œFASEB journal · 2010 · 149 citations
    22. Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018 · 37 citations
    23. STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction Journal of Investigative Dermatology · 2016 · 32 citations
    24. Generation of bioengineered feather buds on a reconstructed chick skin from dissociated epithelial and mesenchymal cells Development Growth & Differentiation · 2016 · 10 citations
    25. Regeneration of hair and other skin appendages: A microenvironment‐centric view Wound Repair and Regeneration · 2016 · 10 citations
    26. Mutation of the GDP-Fucose Biosynthesis Gene gmds Increases Hair Cell Number and Neuromast Regenerative Capacity in Zebrafish International Journal of Molecular Sciences · 2025 · 1 citations
    27. Effects of photobiomodulation at various irradiances on normal and dihydrotestosterone‐treated human hair dermal papilla cells in vitro Journal of Biophotonics · 2023 · 1 citations
    28. Lateral plate mesoderm directs human amnion and ventral skin organoid formation bioRxiv (Cold Spring Harbor Laboratory) · 2025
    29. Decision letter: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation 2018
    30. 1362 The role of Fgf20 in establishing the hair follicle dermal condensate Journal of Investigative Dermatology · 2018