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Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The document concludes that proper diagnosis and treatment of common scalp disorders are important for both physical and psychological health.

Fat cells are important for tissue repair and stem cell support in various body parts.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.