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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The Rotterdam Study aims to understand various diseases in older adults.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Probiotic bacteria improved skin and hair health in aged mice.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Liposomes could improve how skin care products work but are costly and not very stable.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.

Treatments for melanin disorders exist, but more effective options needed.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.