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Honokiol might help reduce male skin aging by maintaining testosterone levels.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

The document describes various skin conditions, their features, and treatments but lacks detailed study size information.

Skin aging reflects overall body aging and can indicate internal health conditions.

Hutchinson-Gilford Progeria Syndrome causes rapid aging from a genetic mutation, with no cure but ongoing research into potential treatments.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The Rotterdam Study aims to understand various diseases in older adults.

Androgens can both increase and decrease hair growth in different parts of the body.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Cathepsin L is essential for normal hair growth and development.