63 citations
,
January 2017 in “Annals of Dermatology” More research is needed to understand alopecia areata severity.
62 citations
,
October 2017 in “JAMA facial plastic surgery” This study reported that using condensed nanofat combined with fat grafts significantly improved the aesthetic and functional aspects of atrophic facial scars in 20 patients, as assessed by both patients and plastic surgeons using the Patient and Observer Scar Assessment Scale.
61 citations
,
April 2023 in “Bioactive Materials” This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.
60 citations
,
November 2009 in “General and Comparative Endocrinology” The researchers reported that during early embryogenesis and larval development in Silurana tropicalis, inhibiting steroidogenic enzymes cyp19 and srd5beta affects genes related to thyroid and reproductive systems.
60 citations
,
April 2003 in “Human Reproduction” This study found that Czech women with polycystic ovary syndrome in their thirties had a significantly worse cardiovascular risk profile compared to a control group, independent of obesity.
60 citations
,
February 1992 in “British Journal of Dermatology” In this study, serum from patients with alopecia areata or universalis did not affect hair growth in transplanted scalp skin grafts on nude mice, despite increased deposition of immunoreactants.
58 citations
,
February 2018 in “Journal of cosmetic dermatology” This review explores how estrogens influence skin health and attractiveness in women, particularly with aging, but it reports no new clinical findings.
57 citations
,
February 2016 in “Dermatologic surgery” This review identifies excessive sebum, decreased elasticity, and increased hair follicle volume as key factors contributing to enlarged skin pores, emphasizing the need for individualized treatment based on underlying causes.
57 citations
,
January 2004 in “Journal of Endocrinology” This study found no support for the idea that male-pattern baldness in female-to-male transsexuals indicates an increased risk of coronary heart disease through androgenic effects on classic risk factors.
55 citations
,
July 2020 in “International Wound Journal” This study evaluated the feasibility of a single-center, three-arm trial to assess fat grafting with or without PRP for diabetic foot ulcers, finding high patient engagement and indicating that a multi-center trial could be safe and feasible.
53 citations
,
January 2017 in “BioMed research international” This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.
53 citations
,
October 2018 in “Aesthetic Surgery Journal” This study found that Google Trends data on search terms like "eyelid plastic surgery," "facelift," and "rhinoplasty surgery" significantly correlated with actual US surgery volumes, highlighting its potential use for plastic surgeons in marketing and advertising decisions.
53 citations
,
July 2009 in “Journal of the American Academy of Dermatology” This study suggests that cigarette smoking is a significant risk factor for hidradenitis suppurativa in Polish patients, but other potential contributors like obesity and diabetes showed no strong associations.
51 citations
,
November 2005 in “Journal of Medical Primatology” This study observed that hair loss in captive rhesus macaques varies with season, sex, and housing conditions, and is significantly correlated with HPA axis activity as indicated by faecal cortisol metabolites.
49 citations
,
April 2007 in “Pediatric Dermatology” This study describes a family with uncombable hair syndrome, suggesting autosomal dominant inheritance, and reports that oral biotin improved hair appearance in two young patients.
49 citations
,
January 2004 in “Dermatology” This study found that men with a paternal history of hair loss were significantly more likely to experience hair loss themselves.
48 citations
,
February 2016 in “Scientific Reports” This study reports the creation of rat liver stem cell lines that can differentiate into hepatocytes and suggests they might be useful for pharmacological and regenerative medicine applications.
46 citations
,
December 2014 in “Journal of The American Academy of Dermatology” This study found that smoking, obesity, and family history are significant risk factors for premature hair graying in young men.
46 citations
,
January 2008 in “Journal of cosmetic dermatology” Caffeine and siloxanetriol alginate caffeine in emulsion form can reduce fatty cell size and number, potentially treating cellulite effectively.
44 citations
,
October 2017 in “Scientific Reports” This study found that far-infrared radiation preconditioning significantly enhanced the proliferation, survival, and migration of bone marrow-derived stem cells in vitro, indicating potential therapeutic benefits for cardiac ischemia treatment.
43 citations
,
June 2016 in “Clinics in Plastic Surgery” This article reviews technical aspects of using autologous fat transfer for facial rejuvenation and examines existing evidence for stem cell and platelet-rich plasma therapies in aesthetic practice, reporting no new results.
40 citations
,
July 2019 in “Journal of Investigative Dermatology” In this study, knockout mice lacking the Cyp4f39 gene showed severe skin barrier dysfunction and high early mortality, suggesting its critical role in skin barrier formation and insights into ichthyosis pathogenesis.
40 citations
,
August 2021 in “International Journal of Molecular Sciences” This review discusses the role of fascial mobilization in wound healing and its potential implications for treating chronic skin wounds and scarring, but reports no new clinical results.
40 citations
,
June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” This study revealed that deficiency in the enzyme FA2H in mice affected sebaceous gland function, altered sebum composition, and caused cycling alopecia, highlighting FA2H's role in hair follicle homeostasis.
40 citations
,
November 2007 in “Journal of oral and maxillofacial surgery” This study concluded that the overall incidence of complications from superficial plane facelift surgery is very low, with postoperative hematoma being the most common issue.
39 citations
,
October 2018 in “Aesthetic surgery journal” This review discusses nonsurgical techniques for facial masculinization and feminization in transgender patients and reports no new clinical findings, utilizing data from analogous procedures in cisgender individuals.
39 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The study concluded that fatty acid transport protein 4 in epidermal keratinocytes is crucial for maintaining normal skin structure, as its deficiency led to hyperkeratosis and epidermal barrier disruption in mice.
38 citations
,
May 2021 in “International Journal of Infectious Diseases” This study found that lower testosterone levels in male COVID-19 patients were associated with greater disease severity and longer hospital stays.
38 citations
,
February 2012 in “Aesthetic Surgery Journal” This article discusses the importance of individualized treatment plans based on the morphological characteristics of the aging face in surgical rejuvenation, but it provides no new findings.
38 citations
,
March 2010 in “Medicine” In this study, researchers found that hepatitis C virus infection is a significant risk factor for sporadic porphyria cutanea tarda, suggesting familial cases might be more prevalent in areas with low hepatitis C infection rates.