October 2020 in “Journal of bio innovation” In this study, DanEra, an herbal hair tonic from Pomegranate and Beetroot extracts, showed equivalent effectiveness to the standard drug Ketoconazole in microbiological tests and provided significant relief from severe dandruff in all volunteers within 10 days.
September 2020 in “Pharmauho/Pharmauho : Jurnal Farmasi, Sains dan Kesehatan” This study concluded that hair tonic formulated with galangal rhizome and Aloe vera extract was stable according to the Indonesian National Standard, showing consistent organoleptic, pH, and viscosity characteristics after stability testing.
January 2020 in “Ayurline: IJ-RIM” This study found that Eclipta alba Hassk. (Bhrungraj) significantly inhibited the growth of human liver cancer cells, suggesting its potential as an anticancer agent.
January 2020 in “Journal of St. Marianna University” This study found that human placenta extract may enhance hair growth by increasing PG-E2 and PG-F2a production while decreasing PG-D2 levels in cultured hair follicle keratinocytes.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that the developed hydrogel nanoparticles showed potential for enhancing hair growth by effectively delivering and releasing hair growth-promoting herbal extracts into hair follicles.
September 2019 in “Journal of Investigative Dermatology” This study found that a combination of botanical extracts from Pisum sativum and Salvia hispanica reduced oxidative damage, re-balanced scalp oiliness, and improved scalp hydration and barrier function after pollution exposure.
May 2019 in “Eurasian Journal of Biosciences” In this study, researchers observed that fenugreek aqueous extract was more effective than its alcohol extract in inhibiting the growth of bacteria associated with acne, particularly gram-positive bacteria like Staphylococcus epidermidis and Staphylococcus aureus.
April 2019 in “Majalah Obat Tradisional” This study found that adding menthol to Phyllanthus niruri ethanol extract gel enhanced hair growth and thickness in rats.
March 2019 in “The International Journal of Advanced Smart Convergence” This study found that topical radish saponin significantly increased hair density and follicle formation in nude mice predisposed to pattern balding.
January 2019 in “International Journal of Plant Animal and Environmental Sciences” This study found that a 50% ethanol extract from marine green alga Chlamydomonas sp. W80 exhibited several bioactive properties, including skin lightening and hair growth promotion effects, with potential implications for bioenergy and high-value coproducts.
August 2018 in “Journal of the Korean Chemical Society” This study found that ethanol extract from the traditional Korean medicinal plant Anemarrhena asphodeloides effectively promoted hair growth in mice without altering serum composition, suggesting its potential as a hair growth-promoting agent.
This study tested a natural hair dye made from papaya seed extract, celery leaf, and avocado, finding color change in animal hair but also noting tissue changes like hyperkeratosis.
This study found that topical application of Sinsun-yukza-hwan extract significantly increased hair density and thickness in a mouse alopecia model and enhanced expression of growth-related genes.
In this animal study, leaf extracts of Kalanchoe pinnata increased hair length in rabbits in a concentration-related manner, surpassing minoxidil at the highest concentration, though hair mass was unaffected.
January 2018 in “BiblioBoard Library Catalog (Open Research Library)”
January 2018 in “International journal for pharmaceutical research scholars” In this study, topical application of tonic preparations containing 5% ethanol extract of Phyllanthus niruri to shaved mice showed potential as a hair growth enhancer, as indicated by observations of increased hair length and weight over a 21-day period.
This study suggests that ethyl acetate extract of Equisetum debile may be effective for functional food and nutraceutical use due to its strong 5α-reductase, IL-6 inhibition, and lipid peroxidation activities without cytotoxic effects.
April 2016 in “Journal of Investigative Dermatology” This study found that secreted factors from skin-derived precursors, especially those pre-treated with jasmine extract, enhanced keratinocyte growth and influenced reconstructed human epidermis thickness in lab experiments.
This study investigated whether combinations of green tea leaf and gotukola extracts could act as a hair growth stimulant but reports no definitive results on the most effective combination.
January 2015 in “CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION)” This study developed a rapid and reliable ultra high performance liquid chromatography method for analyzing 17 key ingredients in hair growth cosmetics.
December 2014 in “Research and Reviews: Journal of Pharmacology and Toxicological Studies” This study found that applying pet ether extract of Brassica oleracea to rats' skin promoted earlier and longer anagen phases in hair growth, outperforming 1% minoxidil.
May 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that treating hair follicular stem cells with tissue extract from 10-day-old mouse embryos significantly enhanced their differentiation into neural cells, particularly with higher extract concentrations.
February 2014 in “PubMed” This study found that Lycopersicon esculentum extracts applied to mice promoted hair growth similarly to minoxidil and increased growth factor expression, suggesting potential in hair loss treatments without skin irritation.
In a laboratory setting, this study reported that the n-butanol fraction of Urtica laetevirens Maxim. water extracts significantly inhibited 5α-reductase activity.
This study found that a 10% hibiscus leaf extract hair tonic demonstrated better hair growth activity than 2% minoxidil in rabbits but caused eye irritation.
August 2013 in “Han'gug saengmul gonghag hoeji/KSBB journal” This study found that callus extracts from apple 'Hirosaki' may improve collagen synthesis, hair follicle cell proliferation, and possess significant anti-inflammatory properties.
Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.
This study found that green tea extract showed more effective wound healing in rabbits with direct fire burns than an antibiotic ointment, particularly improving the skin's normal appearance and recovery rate.
March 2009 in “Journal of Biomedical Research” In this study, herbal extract mixtures applied to mice accelerated hair regrowth compared to a control group, suggesting potential hair-growing properties.
January 2008 in “วารสารการแพทย์และวิทยาศาสตร์สุขภาพ (Journal of Medicine and Health Sciences)” This study found that extracts from Clitorea ternatea and Citrus hystrix promoted human hair follicle growth in vitro, although high concentrations of Citrus hystrix extract inhibited growth.