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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Researchers created human hair follicles using a new method that could help treat hair loss.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

New effective scar treatments are urgently needed due to the current options' limited success.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Zinc is effective for treating various skin conditions, including warts and acne.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

CDP is crucial for lung and hair follicle cell development.

Low iron levels may be linked to some types of hair loss in women.

Latanoprost can make eyelashes longer, thicker, and darker.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.