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    Did you mean Ex Vivo Culture?
    Glossary Ex Vivo Culture

    growing cells or tissues outside their original biological context

    Ex Vivo Culture refers to the process of growing or maintaining cells, tissues, or organs outside of their original biological context, typically in a controlled laboratory environment. This technique allows researchers to study biological processes in a more natural state than in vitro (in a petri dish) while still being able to manipulate and observe the sample closely. For example, hair follicles can be cultured ex vivo to study hair growth and alopecia treatments.

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    1. Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System Methods in molecular biology · 2010 · 13 citations
    2. Prostaglandin F2α stimulates the growth of human intermediate hair follicles in ex vivo organ culture with potential clinical relevance Frontiers in Physiology · 2025
    3. Human hair growth ex vivo is correlated with in vivo hair growth: selective categorization of hair follicles for more reliable hair follicle organ culture Archives of Dermatological Research · 2005 · 27 citations
    4. Ex-vivo Hair Growth Promotion Efficacy of Biofield Energy Treated Williams Medium E using Vibrissae Hair Follicle Organ Culture Zenodo (CERN European Organization for Nuclear Research) · 2018
    5. Identification of human hair follicle antigens targeted in the presumptive autoimmune hair follicle disorder alopecia areata and their potential functional relevance in vitro : methods development for isolation and identification of alopecia areata-relevant human hair follicle antigens using a proteomics approach and their functional assessment using an ex vivo hair follicle organ culture model Bradford Scholars (University of Bradford) · 2008
    6. 581 Spontaneous, Intrinsic Aging in Organ-Cultured Human Skin as Novel Ex Vivo Assay to Test Candidate Anti-Aging Actives Journal of Investigative Dermatology · 2022
    7. Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion Lab on a Chip · 2013 · 208 citations
    8. Limitations of human occipital scalp hair follicle organ culture for studying the effects of minoxidil as a hair growth enhancer Experimental Dermatology · 2004 · 30 citations
    9. Non-thermal atmospheric pressure plasma activates Wnt/β-catenin signaling in dermal papilla cells Scientific Reports · 2021 · 24 citations
    10. Hair Growth Promoting Effect of Urticadioica L Central Asian journal of medical sciences (Print) · 2018
    11. Panax ginseng extract antagonizes the effect of DKK-1-induced catagen-ike changes of hair follicles International Journal of Molecular Medicine · 2017 · 15 citations
    12. 1372 Biological effects of electrical epilation on human hair follicles and perifollicular skin ex vivo 2018
    13. Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata Frontiers in Medicine · 2026
    14. Topically applied thyroid hormones stimulate hair growth in organ-cultured human scalp skin 2024
    15. Engineered Nanovesicles from Fibroblasts Modulate Dermal Papillae Cells In Vitro and Promote Human Hair Follicle Growth Ex Vivo Cells · 2022 · 4 citations
    16. A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond 5‐alpha reductase inhibition: Insights from human hair follicle organ culture International Journal of Cosmetic Science · 2025
    17. Hair Growth Promoting Effects of 15-Hydroxyprostaglandin Dehydrogenase Inhibitor in Human Follicle Dermal Papilla Cells International Journal of Molecular Sciences · 2024
    18. Human hair follicle organ culture: theory, application and perspectives Experimental Dermatology · 2015 · 130 citations
    19. Vitamins and their derivatives synergistically promote hair shaft elongation ex vivo via PlGF/VEGFR-1 signalling activation Journal of dermatological science · 2022 · 1 citations
    20. Sensory Reinnervation of Human Skin by Human Neural Stem Cell‒Derived Peripheral Neurons Ex Vivo 2021 · 7 citations
    21. 503 A new chemosensory control of human hair growth: Olfactory receptor OR10J1 stimulation promotes scalp hair follicle growth and progenitor cell generation ex vivo Journal of Investigative Dermatology · 2024
    22. 422 Human hair follicles express PD-L1, whose expression is down-regulated by EGFR and MEK inhibitors ex vivo. A potential mechanism for EGFR inhibitor induced sterile folliculitis Journal of Investigative Dermatology · 2019
    23. 1432 IL-9/IL-9R signaling as a novel regulator of human hair follicle growth and immune privilege Journal of Investigative Dermatology · 2023
    24. Shikimic acid, a mannose bioisostere, promotes hair growth with the induction of anagen hair cycle Scientific Reports · 2019 · 35 citations
    25. Divergent proliferation patterns of distinct human hair follicle epithelial progenitor niches in situ and their differential responsiveness to prostaglandin D2 Scientific Reports · 2017 · 21 citations
    26. 1362 The role of Fgf20 in establishing the hair follicle dermal condensate Journal of Investigative Dermatology · 2018
    27. 621 An apple stem cell-derived extract increases epithelial stem cells number in the hair follicle bulge Journal of Investigative Dermatology · 2019
    28. 52993 Regulatory γδ T cells protect human scalp hair follicles from alopecia areata in vivo Journal of the American Academy of Dermatology · 2024
    29. Intrinsic activation of cell growth and differentiation in ex vivo cultured human hair follicles by a transient endogenous production of ROS Scientific reports · 2019 · 9 citations
    30. 1370 17β-estradiol may control human HF growth also via up-regulating the expression of cannabinoid receptor type1 expression 2018