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Transgender and gender-diverse adults on hormone therapy often face drug-hormone interactions, especially with multiple psychotropic medications.

Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Testosterone's effects on COVID-19 are unclear and need more research.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

Hormonal imbalances during menopause may significantly contribute to Frontal Fibrosing Alopecia.

Pregnancy often causes skin changes like darker nipples, swelling in feet, and stretch marks.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

Birth control pills can help reduce mild to moderate acne in women.

A male with aromatase deficiency improved bone health with estradiol treatment.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Acne and other skin conditions can indicate internal diseases like Polycystic Ovary Syndrome (PCOS), and early treatment can prevent long-term issues.

Most doctors know the thrombosis risk with Cyproterone/Ethinylestradiol, but some lack details on less common risks and patient instructions; educational materials are underused but useful.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.