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Men and women experience skin aging differently due to changes in sex hormone levels with age.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Finasteride doesn't affect erections much, but may decrease libido in men.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Hormone therapy for trans individuals is effective and generally safe in the short term.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

High doses of finasteride cause cell growth and tumors in mice.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Secondary aesthetic surgeries for gender reassignment are generally satisfying and advance overall aesthetic surgery techniques, but psychological support is important.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Finasteride causes abnormal growth in male mice cells at high doses.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Stress hormones like cortisol may trigger psoriasis flare-ups.

Insulin resistance is linked to larger thyroid volume in patients with polycystic ovary syndrome.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Both estrogens and androgens are important for health in both males and females.

Uterine transplants for transgender women are feasible but need more research.