Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

The study characterized the transcriptional changes in porcine SKP cells transitioning to fibroblast-like cells, indicating potential roles for specific signaling pathways in this cell fate transition.

This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.

This narrative review reports that metformin, traditionally used for type 2 diabetes management, may offer therapeutic benefits for various skin disorders, such as acne, rosacea, and psoriasis, due to its anti-inflammatory and other beneficial properties, warranting further exploration in dermatology.

This review highlighted the role of microRNAs (miRNAs) in gouty arthritis, emphasizing their potential influence on disease progression through immune and inflammatory regulation, and their prospective use in diagnosis, prognosis, and therapy.

This study found that a specific fragment of AIMP1, secreted by hair follicle stem cells, activated dermal papilla cells, leading to enhanced hair regrowth and maintenance in mice.

This study analyzed watercress oil and confirmed its phytochemical profile, UV absorption properties, and potential efficacy for hair growth, supporting traditional hot oil applications.

This study found that in a mouse model of Leigh syndrome, rapamycin alters brain proteome and may extend survival by targeting protein kinase C.

This review discusses various treatments for adult acne in women, including topical, systemic, and alternative therapies, and reports no new clinical results.

This study introduced the concept of spatiotemporal clocks to understand how different phases of mammalian wound healing are coordinated, with a focus on the spatial domains and oscillatory molecular signals involved, while highlighting the potential for regenerative therapeutic strategies.

This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.

This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.

This review compiles current experimental research on Alzheimer's and cognitive impairment models, highlighting the potential of *Polygonum multiflorum* for treating neurological disorders and suggesting a foundation for future clinical trials.

This review explores the potential role of caveolin-1 in cicatricial alopecia, particularly frontal fibrosing alopecia, and discusses possibilities for targeted therapies without providing new research results.

This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.

This study found that activating TRPV4 in the skin of mice induced hair follicle regeneration by promoting anagen transition, suggesting potential treatment strategies for hair loss.

This study compiled an archive of 684 genes associated with monogenic hair disorders, identifying previously unrecognized components of Hippo signaling and proposing a new biologically-grounded disease taxonomy.

This paper discusses the challenges of diagnosing drug eruptions, emphasizing the nonspecific patterns and unclear pathomechanisms, and calls for further research using new biologic drugs to understand these reactions better.

In this study, researchers using single nuclei RNA-sequencing found that fibroblasts in deeper layers of mouse skin expressed higher levels of pro-inflammatory genes post-wounding compared to other cells, highlighting their significant role in early inflammation and tissue repair processes.

This study demonstrates that Puerariae Lobatae Radix may regulate skin lipid metabolism by inhibiting sebaceous gland growth and reducing triglyceride secretion, highlighting its therapeutic potential for sebaceous gland-related conditions.

This study presents a detailed overview of lymphatic vessel development and highlights the role of abnormal lymphangiogenesis in various diseases, suggesting that targeting lymphangiogenic factors may improve treatment strategies.

This paper provides a comprehensive review of melanocytes' roles in skin biology, focusing on their pigmentation and immune functions, and suggests potential research opportunities for preventing and treating skin disorders.

This study suggests that in mice, plasmalogens may enhance hair growth by activating TRPC4 channels, which increases calcium influx and subsequently stimulates AMPK in hair follicles.

This summary reviews the conflicting reports regarding 17β‐estradiol's effects on hair follicle growth, highlighting potential estrogen receptor-mediated impacts and calling for further research.

This study used computational modeling to identify key genes and miRs involved in cardiac aging, finding a strong relationship supported by literature and some experimental validation in aged mouse hearts.

This study found that EGFR inhibitors and ligands did not significantly affect the expression of inflammatory biomarkers in cultured sebocytes, except for a notable increase in IL-1 expression with EGF treatment.

This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.

In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.

This review examines the traditional uses and biological activities of Glycyrrhiza glabra in Ayurveda, but reports no new clinical results; the authors identify a gap in evidence supporting its medicinal potential.

This review discusses the role of the mTORC1 pathway in acne pathogenesis in relation to diet and reports no new results.

This study demonstrates that the amino-terminally shortened KGF-1 variant with 135 residues maintains biological activity, suggesting it may serve as an alternative to the original KGF-1 for certain therapeutic applications.