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    Glossary ERK inhibitors

    drugs that block proteins involved in cell signaling

    ERK inhibitors are drugs or molecules that block the activity of ERK (Extracellular signal-Regulated Kinases), which are proteins involved in sending signals within cells. These signals can control various functions, including cell growth and division. By inhibiting ERK, these drugs can potentially treat conditions like cancer, where cell growth is uncontrolled, or even certain types of hair loss by affecting the pathways that regulate hair follicle activity.

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    Research 30 of 1000+

    1. VEGF induces proliferation of human hair follicle dermal papilla cells through VEGFR-2-mediated activation of ERK Experimental Cell Research · 2012 · 120 citations
    2. Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632 Frontiers in cell and developmental biology · 2021 · 16 citations
    3. Dihydrotestosterone Induces Keratinocyte Apoptosis by Activating ERK Signaling In Vivo · 2026
    4. Hair Growth Promoting Effects of 15-Hydroxyprostaglandin Dehydrogenase Inhibitor in Human Follicle Dermal Papilla Cells International Journal of Molecular Sciences · 2024
    5. The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors Postępy Dermatologii i Alergologii · 2017 · 18 citations
    6. Protopanaxatirol type ginsenoside Re promotes cyclic growth of hair follicles via inhibiting transforming growth factor β signaling cascades Biochemical and Biophysical Research Communications · 2016 · 14 citations
    7. Antimelanogenic effect of ginsenoside Rg3 through extracellular signal-regulated kinase-mediated inhibition of microphthalmia-associated transcription factor Journal of Ginseng Research · 2015 · 33 citations
    8. Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling Frontiers in bioengineering and biotechnology · 2022 · 8 citations
    9. 873 The effect of Cilostazol on hair growth: A novel therapeutic option for the treatment of hair loss Journal of Investigative Dermatology · 2017 · 1 citations
    10. Cutaneous Drug Eruptions Associated with the Use of New Oncological Drugs 2012 · 29 citations
    11. 691 Topical curcumin promotes induction of the murine hair cycle 2016 · 3 citations
    12. Role and Mechanisms of Phytochemicals in Hair Growth and Health Pharmaceuticals · 2023 · 2 citations
    13. 546 Epidermal growth factor receptor as a key regulator of the immune privilege Journal of Investigative Dermatology · 2022
    14. Sorafenib-induced eruption resembling pityriasis rubra pilaris Journal of the American Academy of Dermatology · 2011 · 21 citations
    15. When bugs and drugs conspire: driving acneiform skin toxicity 2020 · 1 citations
    16. Cutaneous adverse effects of targeted therapies Journal of the American Academy of Dermatology · 2015 · 149 citations
    17. An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice ( <i>Acomys</i> ) Science Advances · 2023 · 1 citations
    18. Chemical Constituents from Osmanthus fragrans var. aurantiacus Makino with Their In Vitro and In Silico Studies Target Anti-Inflammation by Suppressing ERK 1/2 MAPK Signaling International Journal of Molecular Sciences · 2025
    19. miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades Journal of Advanced Research · 2024 · 15 citations
    20. Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK-3β signaling pathway BMC Complementary and Alternative Medicine · 2019 · 10 citations
    21. Biofabrication of silver nanoparticles using Ostericum koreanum plant extract for treatment of allergic rhinitis in nursing care Materials Research Express · 2020 · 5 citations
    22. [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs Biochemical Pharmacology · 2007 · 26 citations
    23. The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K-/Akt-mediated tyrosinase degradation Experimental Dermatology · 2015 · 15 citations
    24. Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells Biomolecules & Therapeutics · 2019 · 9 citations
    25. Hair Growth Effect and the Mechanisms of Rosa rugosa Extract in DHT-Induced Alopecia Mice Model International Journal of Molecular Sciences · 2024
    26. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    27. Preconditioning with far-infrared irradiation enhances proliferation, cell survival, and migration of rat bone marrow-derived stem cells via CXCR4-ERK pathways Scientific Reports · 2017 · 44 citations
    28. Undariopsis peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways Marine Drugs · 2017 · 27 citations
    29. Involvement of Activation of Mitogen-Activated Protein Kinase (MAPK)/Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway in Proliferation of Urethral Plate Fibroblasts in Finasteride-Induced Rat Hypospadias Medical Science Monitor · 2018 · 10 citations
    30. Wheat Sprout Extract Stimulates Cell Proliferation via Phosphorylation of ERK and Akt in Human Dermal Papilla Cells 2017